Evidence map›Paper›PMID 33085046›Full record

ArticleEuropean geriatric medicine2021

BMI, functional and cognitive status in a cohort of nonagenarians: results from the Mugello study.

Monica Dinu, Barbara Colombini, Giuditta Pagliai, Federica Vannetti, Guido Pasquini, Raffaello Molino Lova, Francesca Cecchi, Sandro Sorbi, Francesco Sofi, Claudio Macchi and 1 more

Open access · hybridAbstract read
In one paragraph

Article in European geriatric medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Monica DinuDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy. monica.dinu@unifi.it.ORCID 0000-0003-1687-2527
Barbara ColombiniDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Giuditta PagliaiDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Federica VannettiDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Guido PasquiniDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Raffaello Molino LovaDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Francesca CecchiDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Sandro SorbiDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Francesco SofiDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Claudio MacchiDon Carlo Gnocchi Foundation Florence, Onlus IRCCS, Florence, Italy.
Mugello Study Working Group
Don Carlo Gnocchi Foundation · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study of the relationship between body weight and health in old age has attracted increasing interest. The aim of the present study is to investigate the association of body mass index (BMI) with functional and cognitive status in a group of nonagenarians.

methodsWe analyzed 475 participants (348 women, 127 men; median age 92 years) from the Mugello study. Participants were evaluated through laboratory, instrumental examinations and questionnaires.

resultsBy grouping the participants according to BMI categories, a better perception of health and nutritional status and a lower prevalence of sarcopenia (p < 0.05) were observed in participants with overweight and obesity compared to participants with normal weight or underweight. Concerning functional and cognitive measures, overweight and obese participants showed significantly worse performance on short physical performance battery and timed up and go tests and better performance on the mini-mental state examination (MMSE). As regards the other tests performed, no statistically significant differences were observed. In a multivariate logistic regression analysis adjusted for possible confounding factors, participants with BMI ≥ 30 kg/m

conclusionOur results support the hypothesis that in nonagenarians, a higher BMI is associated with better cognitive ability. Further studies are needed to explore the mechanisms underlying this association.

Indexed as

OverweightThinnessAged, 80 and overBody Mass IndexBody WeightCognitionFemaleHumansMaleBMICognitive statusFunctional statusNonagenariansObesity paradox

Identifiers

PMID33085046
PMCPMC7990833
OpenAlexW3093909369

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.