Evidence map›Paper›PMID 33084318›Full record

ArticleJournal of the American Chemical Society2020

Probing Nanoscale Diffusional Heterogeneities in Cellular Membranes through Multidimensional Single-Molecule and Super-Resolution Microscopy.

Rui Yan, Kun Chen, Ke Xu

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 70 citations in OpenAlex.

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  2. ACS central science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rui YanDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0003-3391-133X
Kun ChenDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Ke XuDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0002-2788-194X
Chan Zuckerberg Initiative (United States) · US

Funding

Intracellular phase separation at the nanoscale: a functional super-resolution approachDP2GM132681 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI XU, KE · 2018 to 2018
$2.4M
NIGMS NIH HHS DP2 GM132681
6 · The paper itself

Abstract

Diffusion properties notably determine the behavior of biomembranes. Here we report the concurrent nanoscale fine-mapping of membrane topography, diffusivity, and packing order in live mammalian cells through a synergy of single-molecule and super-resolution methods. By identifying a bright, lipophilic fluorescence turn-on probe that enables sustained single-molecule imaging of cellular membranes under stroboscopic excitation, we accumulate the positions and transient displacements of >10

Indexed as

AnimalsCell MembraneChlorocebus aethiopsCholera ToxinCOS CellsDiffusionEndoplasmic ReticulumFluorescent DyesMicroscopy, FluorescenceNanotechnologySingle Molecule ImagingCholera ToxinFluorescent Dyes

Identifiers

PMID33084318
PMCPMC8447239
OpenAlexW3093747306

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.