Evidence map›Paper›PMID 33084241›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2021

Long-term community noise exposure in relation to dementia, cognition, and cognitive decline in older adults.

Jennifer Weuve, Jennifer D'Souza, Todd Beck, Denis A Evans, Joel D Kaufman, Kumar B Rajan, Carlos F Mendes de Leon, Sara D Adar

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Review
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  8. Review
  9. A silent hazard-noise in the veterinary sector: a scoping review.Occupational medicine (Oxford, England) · 2026
    Article
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  17. Impact of Residential Noise Exposure on Neurological Health: A Systematic Scoping Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jennifer WeuveSchool of Public Health, Boston University, Boston, Massachusetts, USA.
Jennifer D'SouzaSchool of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Todd BeckInstitute for Healthy Aging, Rush University, Chicago, Illinois, USA.
Denis A EvansInstitute for Healthy Aging, Rush University, Chicago, Illinois, USA.
Joel D KaufmanSchool of Public Health, University of Washington, Seattle, Washington, USA.
Kumar B RajanDepartment of Public Health Sciences, UC Davis, Davis, California, USA.
Carlos F Mendes de LeonSchool of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Sara D AdarSchool of Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5M
Risk Factors for Incident Alzheimer's Disease in a Biracial CommunityR01AG011101 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI EVANS, DENIS A · 1993 to 2010
$24.7M
Preserving Cognitive Resilience: A Biracial Parent-Offspring Study (18-4674) - Feasibility StudyR01AG058679 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI EVANS, DENIS A, RAJAN, KUMAR B. · 2019 to 2024
$13.8M
Air pollution and noise exposures in relation to dementia: from brain imaging markers to clinical diseaseR01AG065359 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WEUVE, JENNIFER · 2020 to 2023
$2.3M
Air pollution, the social environment, and Alzheimer's disease: Risk and resilience in the Ginkgo Evaluation Memory StudyRF1AG057033 · NIA · UNIVERSITY OF WASHINGTON · PI FITZPATRICK, ANNETTE L., KAUFMAN, JOEL DANIEL · 2017 to 2017
$2.3M
Factors Influencing Decline in AD Trends in a Biracial Population StudyRF1AG057532 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RAJAN, KUMAR B. · 2017 to 2017
$1.7M
Nonlinear Models of Cognition Preceding AD in a Biracial Population SampleR01AG051635 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI RAJAN, KUMAR B. · 2016 to 2020
$1.5M
NIA NIH HHS R01 AG011101NIA NIH HHS R01 AG051635NIA NIH HHS R01 AG058679NIA NIH HHS R01 AG065359NIA NIH HHS RF1 AG057033NIA NIH HHS RF1 AG057532NIEHS NIH HHS P30 ES007033
6 · The paper itself

Abstract

introductionExposure to noise might influence risk of Alzheimer's disease (AD) dementia.

methodsParticipants of the Chicago Health and Aging Project (≥65 years) underwent triennial cognitive assessments. For the 5 years preceding each assessment, we estimated 5227 participants' residential level of noise from the community using a spatial prediction model, and estimated associations of noise level with prevalent mild cognitive impairment (MCI) and AD, cognitive performance, and rate of cognitive decline.

resultsAmong these participants, an increment of 10 A-weighted decibels (dBA) in noise corresponded to 36% and 29% higher odds of prevalent MCI (odds ratio [OR] = 1.36; 95% confidence interval [CI], 1.15 to 1.62) and AD (OR = 1.29, 95% CI, 1.08 to 1.55). Noise level was associated with worse global cognitive performance, principally in perceptual speed (-0.09 standard deviation per 10 dBA, 95% CI: -0.16 to -0.03), but not consistently associated with cognitive decline. DISCUSSION: These results join emerging evidence suggesting that noise may influence late-life cognition and risk of dementia.

Indexed as

Residence CharacteristicsAgedAged, 80 and overChicagoCognitionCognitive DysfunctionDementiaFemaleHumansMaleNoiseRisk FactorsagingAlzheimer's diseasecognitioncognitive declinedementiaepidemiologynoise

Identifiers

PMID33084241
PMCPMC8720224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.