Evidence map›Paper›PMID 33083912›Full record

ArticleLasers in medical science2021

Antimicrobial photodynamic therapy against Propionibacterium acnes biofilms using hypericin (Hypericum perforatum) photosensitizer: in vitro study.

Rosmeire Aparecida Barroso, Ricardo Navarro, Carla Roberta Tim, Lucas de Paula Ramos, Luciane Dias de Oliveira, Ângela Toshie Araki, Karina Gonzales Camara Fernandes, Daniela Macedo, Lívia Assis

Abstract read
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In one paragraph

Article in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Azure A as a promising candidate for antimicrobial photodynamic therapy of acne-related bacteria.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
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  4. Divulging the potency of naturally derived photosensitizers in green PDT: an inclusive review Of mechanisms, advantages, and future prospects.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Review
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  16. A narrative review of research progress on the role ofAnnals of translational medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rosmeire Aparecida BarrosoScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil.
Ricardo NavarroScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil.
Carla Roberta TimScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil.
Lucas de Paula RamosInstitute of Science and Technology, Department of Biosciences and Oral Diagnosis, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.
Luciane Dias de OliveiraInstitute of Science and Technology, Department of Biosciences and Oral Diagnosis, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.
Ângela Toshie ArakiDentistry Graduate Program, Universidade Cruzeiro do Sul, São Paulo, SP, Brazil.
Karina Gonzales Camara FernandesScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil.
Daniela MacedoScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil.
Lívia AssisScientific and Technological Institute, Biomedical Engineering Graduate Program, Universidade Brasil, São Paulo, SP, Brazil. livinha_fisio@yahoo.com.br.ORCID http://orcid.org/0000-0002-8343-3375

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne vulgaris is the most recurring skin condition in the world, causing great harm to the physical and psychological well-being of many patients. Antimicrobial photodynamic therapy (aPDT) has broad therapeutic applicability. The purpose was to evaluate in vitro the photodynamic inactivation against Propionibacterium acnes (P. acnes) biofilms by using different concentrations of hypericin (Hypericum perforatum) photosensitizer associated with different energies of low-level laser. The biofilms were placed in 96-well microplates with a 6.4-mm diameter surface, by using standard suspensions (2 × 10

Indexed as

PhotochemotherapyAcne VulgarisAnthracenesAnti-Bacterial AgentsAnti-Infective AgentsBiofilmsHumansHypericumLasersLightPerylenePhotosensitizing AgentsPropionibacterium acnesAnthracenesAnti-Bacterial AgentsAnti-Infective AgentshypericinPerylenePhotosensitizing AgentsAcne vulgarisAntimicrobial photodynamic therapyHypericinPhotochemotherapyPhotosensitizing agents, Propionibacterium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.