Evidence map›Paper›PMID 33083738›Full record

ArticleiScience2020

Lemon Exosome-like Nanoparticles-Manipulated Probiotics Protect Mice from

Chao Lei, Jingyao Mu, Yun Teng, Liqing He, Fangyi Xu, Xiangcheng Zhang, Kumaran Sundaram, Anil Kumar, Mukesh K Sriwastva, Matthew B Lawrenz and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  7. Review
  8. Article
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  16. Nanovesicles fromPharmaceuticals (Basel, Switzerland) · 2025
    Article
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  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 2 countries.

Chao LeiDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Jingyao MuDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Yun TengDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Liqing HeKidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA.
Fangyi XuDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Xiangcheng ZhangDepartment of ICU, the Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, Huaian, Jiangsu 223300, China.
Kumaran SundaramDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Anil KumarDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Mukesh K SriwastvaDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Matthew B LawrenzDepartment of Microbiology & Immunology, University of Louisville, Louisville, KY 40202, USA.
Lifeng ZhangDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Jun YanDepartment of Chemistry, University of Louisville, CTRB 309 505 Hancock Street, Louisville, KY 40202, USA.
Wenke FengDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Craig J McClainDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA.
Xiang ZhangKidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA.
Huang-Ge ZhangRobley Rex Veterans Affairs Medical Center, Louisville, KY 40206, USA.
University of Louisville · US

Funding

Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI James Tristan Collins · 2018 to 2026
$24.4M
Plant exosomes non-coding RNA-mediated anti-inflammatory mechanismsR01AT008617 · NCCIH · UNIVERSITY OF LOUISVILLE · PI HUANG-GE ZHANG · 2016 to 2026
$5.7M
NCCIH NIH HHS R01 AT008617NIGMS NIH HHS P20 GM125504
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Dairy MicrobiologyMicrobial MetabolismNanoparticles

Identifiers

PMID33083738
PMCPMC7530291
OpenAlexW3087719075

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.