Evidence map›Paper›PMID 33083479›Full record

ArticleBioMed research international2020

Levels and Clinical Significance of Regulatory B Cells and T Cells in Acute Myeloid Leukemia.

Qiaofeng Dong, Guosheng Li, Claudio Fozza, Shuli Wang, Shuhuan Yang, Yuqi Sang, Xinguang Liu, Chunyan Chen

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Qiaofeng DongDepartment of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.
Guosheng LiDepartment of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.
Claudio FozzaBlood Diseases Department of Medical, Surgical and Experimental Sciences University of Sassari, Sassari 07100, Italy.
Shuli WangDepartment of Hematology, Heze Municipal Hospital, Heze 274000, China.
Shuhuan YangDepartment of Hematology, Heze Municipal Hospital, Heze 274000, China.
Yuqi SangDepartment of Hematology, Heze Municipal Hospital, Heze 274000, China.
Xinguang LiuDepartment of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.ORCID https://orcid.org/0000-0002-1808-4498
Chunyan ChenDepartment of Hematology, Qilu Hospital, Shandong University, Jinan 250012, China.ORCID https://orcid.org/0000-0002-5919-7624
Heze Municipal Hospital · CNQilu Hospital of Shandong University · CNUniversity of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy, whose immunological mechanisms are still partially uncovered. Regulatory B cells (Bregs) and CD4+ regulatory T cells (Tregs) are subgroups of immunoregulatory cells involved in modulating autoimmunity, inflammation, and transplantation reactions. Herein, by studying the number and function of Breg and Treg cell subsets in patients with AML, we explored their potential role in the pathogenesis of AML. Newly diagnosed AML patients, AML patients in complete remission, and healthy controls were enrolled. Flow cytometry was used to detect percentages of Bregs and Tregs. ELISA was conducted to detect IL-10 and TGF-

Indexed as

AdolescentAdultAgedAged, 80 and overB-Lymphocytes, RegulatoryCase-Control StudiesFemaleForkhead Transcription FactorsGene Expression Regulation, NeoplasticHumansInterleukin-10Leukemia, Myeloid, AcuteLymphocyte CountMaleMiddle AgedRNA, MessengerForkhead Transcription FactorsFOXP3 protein, humanIL10 protein, humanInterleukin-10RNA, MessengerTransforming Growth Factor beta

Identifiers

PMID33083479
PMCPMC7557919
OpenAlexW3092176826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.