Evidence map›Paper›PMID 33083469›Full record

SynthesisBioMed research international2020

Ethnicity-Stratified Analysis of the Association between TNF-

Guanzhong Chen, Bowen Liu, Huanqiang Li, Ziling Mai, Liyao Zhang, Min Li, Liwei Liu, Shiqun Chen, Jiyan Chen, Yong Liu

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Guanzhong ChenGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510000 Guangdong, China.
Bowen LiuGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510000 Guangdong, China.
Huanqiang LiDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000 Guangdong, China.
Ziling MaiGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510000 Guangdong, China.
Liyao ZhangDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000 Guangdong, China.
Min LiDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000 Guangdong, China.
Liwei LiuDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000 Guangdong, China.
Shiqun ChenDepartment of Cardiology, Guangdong Provincial Key Laboratory of Coronary Heart Disease Prevention, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510000 Guangdong, China.ORCID https://orcid.org/0000-0002-2847-019X
Jiyan ChenGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510000 Guangdong, China.ORCID https://orcid.org/0000-0003-1216-9316
Yong LiuGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510000 Guangdong, China.ORCID https://orcid.org/0000-0003-2224-4885
Guangdong Academy of Medical Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral studies have reported conflicting findings regarding the association between tumor necrosis factor-alpha (TNF-

methodsA comprehensive search of observational studies on the association of TNF-

resultsA total of 8 studies involving 6694 patients (2559 cases and 4135 controls) were included. Pooled analysis showed a trend of increased risk between the TNF-

conclusionsThe TNF rs1800629 polymorphism exhibited a trend toward AKI susceptibility with ethnic differences. The relationship was found to be significant among the Asian population, but not among those of Caucasian origin. Additionally, the TNF-

Indexed as

Acute Kidney InjuryAnimalsCase-Control StudiesEthnicityGenetic Predisposition to DiseaseHumansPolymorphism, Single NucleotideTumor Necrosis Factor-alphaTumor Necrosis Factor-alpha

Identifiers

PMID33083469
PMCPMC7556080
OpenAlexW3091492769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.