Evidence map›Paper›PMID 33083451›Full record

ReviewBioMed research international2020

Alginate-Based Platforms for Cancer-Targeted Drug Delivery.

Lili He, Zhenghui Shang, Hongmei Liu, Zhi-Xiang Yuan

Abstract readReview
In one paragraph

Review in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Exploring the anticancer potential of epigallocatechin gallate-loaded sodium alginate nanoparticles: impact of size variation on head and neck cancer cells.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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  6. Natural carrier systems in cancer vaccines and immunotherapy.Human vaccines & immunotherapeutics · 2025
    Review
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  16. Alginate Nanoparticles ContainingInternational journal of biomaterials · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lili He *College of Pharmacy, Southwest Minzu University, Chengdu 610041, China.
Zhenghui Shang *Department of Orthopedics, The People's Hospital of China Three Gorges University, First People's Hospital of Yichang, Yichang 443000, China.
Hongmei LiuCollege of Pharmacy, Southwest Minzu University, Chengdu 610041, China.
Zhi-Xiang YuanCollege of Pharmacy, Southwest Minzu University, Chengdu 610041, China.ORCID https://orcid.org/0000-0001-7809-2580

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an acidic, ocean colloid polysaccharide, alginate is both a biopolymer and a polyelectrolyte that is considered to be biocompatible, nontoxic, nonimmunogenic, and biodegradable. A significant number of studies have confirmed the potential use of alginate-based platforms as effective vehicles for drug delivery for cancer-targeted treatment. In this review, the focus is on the formation of alginate-based cancer-targeted delivery systems. Specifically, some general chemical and physical properties of alginate and different types of alginate-based delivery systems are discussed, and various kinds of alginate-based carriers are introduced. Finally, recent innovative strategies to functionalize alginate-based vehicles for cancer targeting are described to highlight research towards the optimization of alginate.

Indexed as

AlginatesAntineoplastic AgentsDrug CarriersCell Line, TumorDrug Delivery SystemsHumansMicellesNanoparticlesNeoplasmsAlginatesAntineoplastic AgentsDrug CarriersMicelles

Identifiers

PMID33083451
PMCPMC7563048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.