ArticleERJ open research2020
Bronchoscopically delivered microwave ablation in an
Article in ERJ open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The trial behind it
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Transbronchial cryoablation in peripheral lung parenchyma with a novel thin cryoprobe and initial clinical testing.Thorax · 2024Trial
- Comparative study of bronchoscopic and CT-guided percutaneous microwave ablation for inoperable non-small cell lung cancer.Translational lung cancer research · 2025Article
- Histology-validated electromagnetic characterization of ex-vivo ovine lung tissue for microwave-based medical applications.Scientific reports · 2024Article
- Ablation for Single Pulmonary Nodules, Primary or Metastatic. Εndobronchial Ablation Systems or Percutaneous.Journal of Cancer · 2024Article
- Advanced Imaging for Robotic Bronchoscopy: A Review.Diagnostics (Basel, Switzerland) · 2023Review
- Novel Image-Guided Flexible-Probe Transbronchial Microwave Ablation for Stage 1 Lung Cancer.Respiration; international review of thoracic diseases · 2023Article
- The Latest on Lung Ablation.Seminars in interventional radiology · 2022Review
- Augmented fluoroscopy guided transbronchial pulmonary microwave ablation using a steerable sheath.Translational lung cancer research · 2022Article
- Microwave ablation of lung tumors: A probabilistic approach for simulation-based treatment planning.Medical physics · 2021Article
- Transbronchial microwave ablation of lung nodules with electromagnetic navigation bronchoscopy guidance-a novel technique and initial experience with 30 cases.Translational lung cancer research · 2021Article
- Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundPercutaneous microwave ablation is clinically used for inoperable lung tumour treatment. Delivery of microwave ablation applicators to tumour sites within lung parenchyma under virtual bronchoscopy guidance may enable ablation with reduced risk of pneumothorax, providing a minimally invasive treatment of early-stage tumours, which are increasingly detected with computed tomography (CT) screening. The objective of this study was to integrate a custom microwave ablation platform, incorporating a flexible applicator, with a clinically established virtual bronchoscopy guidance system, and to assess technical feasibility for safely creating localised thermal ablations in porcine lungs
methodsPre-ablation CTs of normal pigs were acquired to create a virtual model of the lungs, including airways and significant blood vessels. Virtual bronchoscopy-guided microwave ablation procedures were performed with 24-32 W power (at the applicator distal tip) delivered for 5-10 mins. A total of eight ablations were performed in three pigs. Post-treatment CT images were acquired to assess the extent of damage and ablation zones were further evaluated with viability stains and histopathologic analysis.
resultsThe flexible microwave applicators were delivered to ablation sites within lung parenchyma 5-24 mm from the airway wall
conclusionWe have demonstrated the technical feasibility for safely delivering microwave ablation in the lung parenchyma under virtual bronchoscopic guidance in an
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.