Evidence map›Paper›PMID 33083301›Full record

ArticleIranian journal of public health2020

Efficacy of Pumpkin Ointment in Treatment of Chronic Hand Eczema: A Randomized, Active-Controlled, Double Blind Clinical Trial.

Alemeh Khademi, Parvin Mansuri, Daryoush Pahlevan, Mahbubeh Bozorgi, Malihe Nasiri, Somayeh Hejazi, Zahra Azizian, Laila Shirbeigi

Open access · goldAbstract read
In one paragraph

Article in Iranian journal of public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Foods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Alemeh KhademiDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Parvin MansuriSkin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Daryoush PahlevanResearch Center for Social Determinants of Health, Semnan University of Medical Sciences, Semnan, Iran.
Mahbubeh BozorgiDepartment of Traditional Pharmacy, School of Iranian Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Malihe NasiriDepartment of Biostatistics, School of Paramedical, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Somayeh HejaziSkin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Zahra AzizianDepartment of Dermatology, Iran University of Medical Sciences, Tehran, Iran.
Laila ShirbeigiDepartment of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences · IRStem Cell Technology Research Center · IRIran University of Medical Sciences · IRSemnan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHand Eczema (HE) is chronic skin disease with a high prevalence in population. It has negative impact on the quality of life. Due to the public interest in herbal remedies, we attempt to assess the efficacy of pumpkin ointment in treatment of chronic HE in this research.

methodsThis study was conducted in an outpatient clinic at Imam-Khomeini Hospital in Tehran (Iran) from May 2015 to Nov 2016. We performed a double-blind trial on 60 patients with chronic HE randomized to four groups included pumpkin, betamethasone, eucerin and almond ointment (n=15 for each group) for 28 days. Patients were ordered to apply ointments twice a day. Hand Eczema Severity Index (HECSI) and Dermatology Life Quality Index (DLQI) of the patients were evaluated by a dermatologist on the 1st, 14th and 28th d after the start of treatment.

resultsPatients' DLQI scores in pumpkin and betamethasone group was significant and pumpkin group showed a better response in quality of life (

conclusionAlthough pumpkin ointment showed a better response in patients' DLQI in HE but it was less effective than betamethasone in decreasing HECSI.

Indexed as

AlmondBetamethasoneHand eczemaPersianPumpkinTraditional medicine

Identifiers

PMID33083301
PMCPMC7548497
OpenAlexW3037366443

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.