Evidence map›Paper›PMID 33083084›Full record

ArticleCase reports in transplantation2020

Short Bowel Syndrome and Kidney Transplantation: Challenges, Outcomes, and the Use of Teduglutide.

Elizabeth Abou Diwan, Ankit B Patel, Alex G Cuenca, Nahel Elias, Hannah M Gilligan, Eliot Heher, David E Leaf, David Wojciechowski, Kassem Safa

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in transplantation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Elizabeth Abou DiwanAmerican University of Beirut Medical School, Beirut, Lebanon.
Ankit B PatelDivision of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Alex G CuencaHarvard Medical School, Boston, MA, USA.
Nahel EliasHarvard Medical School, Boston, MA, USA.ORCID 0000-0001-6466-7347
Hannah M GilliganDivision of Nephrology, Massachusetts General Hospital, Boston, MA, USA.
Eliot HeherDivision of Nephrology, Massachusetts General Hospital, Boston, MA, USA.
David E LeafDivision of Renal Medicine, Brigham and Women's Hospital, Boston, MA, USA.
David WojciechowskiDivision of Nephrology, Massachusetts General Hospital, Boston, MA, USA.
Kassem SafaDivision of Nephrology, Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0001-6447-3227
Harvard University · USBrigham and Women's Hospital · USAmerican University of Beirut · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among patients with short bowel syndrome who commonly have kidney disease, kidney transplantation remains challenging. We describe the clinicopathologic course of a 59-year old man with short bowel syndrome secondary to Crohn's disease who underwent a deceased donor kidney transplant that was complicated by recurrent acute kidney allograft injury due to volume depletion from diarrhea, ultimately requiring the placement of permanent intravenous access for daily volume expansion at home resulting in the recovery of allograft function. Teduglutide treatment at 1.8 years post-transplant led to a dramatic decrease in diarrhea. A literature review of similar cases yielded 18 patients who underwent 19 kidney transplants. Despite high rates of complications, at the time of last follow-up (median 2.1 years [0.04-7]), 94% of the patients were still alive and 89% had functioning allografts, with a median eGFR of 37.5 [14-122] ml/min/1.73m

Identifiers

PMID33083084
PMCPMC7557916
OpenAlexW3092084865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.