Evidence map›Paper›PMID 33083063›Full record

ArticleCase reports in critical care2020

Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach.

Jerald Pelayo, Gabriella Pugliese, Grace Salacup, Eduardo Quintero, Adeeb Khalifeh, David Jaspan, Bhavna Sharma

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. COVID-19 and pregnancy: A comparison of case reports, case series and registry studies.European journal of obstetrics, gynecology, and reproductive biology · 2022
    Review
  10. A review of remdesivir for COVID-19 in pregnancy and lactation.The Journal of antimicrobial chemotherapy · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jerald PelayoDepartment of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.ORCID https://orcid.org/0000-0002-5603-7078
Gabriella PuglieseDepartment of Obstetrics and Gynecology, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Grace SalacupDepartment of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Eduardo QuinteroDepartment of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Adeeb KhalifehDivision of Maternal Fetal Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
David JaspanDepartment of Obstetrics and Gynecology, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Bhavna SharmaDepartment of Medicine, Einstein Medical Center Philadelphia, Philadelphia, PA, USA.
Einstein Medical Center Philadelphia · USThomas Jefferson University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapidly expanding cases of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed vulnerable populations, including pregnant women to an unprecedented public health crisis. Recent data show that pregnancy in COVID-19 patients is associated with increased hospitalization, admission of the intensive care unit, and intubation. However, very few resources exist to guide the multidisciplinary team in managing critically ill pregnant women with COVID-19. We report our experience with managing a morbidly obese pregnant woman at 36 weeks' gestation with history of asthma and malignancy who presented with persistent respiratory symptoms at an outside hospital after being tested positive for SARS-CoV-2 polymerase chain reaction (PCR). Early in the course of the hospitalization, patient received remdesivir, convalescent plasma, bronchodilator, systemic steroids, and IV heparin for COVID-19 and concomitant asthma exacerbation and pulmonary embolism. Due to increasing oxygen requirements, she was eventually intubated and transferred to our institution for higher level of care. Respiratory acidosis, severe hypoxemia, and vent asynchrony were managed with vent setting adjustment and paralytics. After 12 hours from spontaneous rupture of her membranes and with stabilization of maternal status, patient underwent a term cesarean delivery for nonreassuring fetal heart tracing. The neonate was discharged on the 2

Identifiers

PMID33083063
PMCPMC7563040
OpenAlexW3093106007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.