Evidence map›Paper›PMID 33082906›Full record

ArticleOxidative medicine and cellular longevity2020

Green-Synthesized Silver Nanoparticles Induced Apoptotic Cell Death in MCF-7 Breast Cancer Cells by Generating Reactive Oxygen Species and Activating Caspase 3 and 9 Enzyme Activities.

Ikram Ullah, Ali Talha Khalil, Muhammad Ali, Javed Iqbal, Waqar Ali, Saud Alarifi, Zabta Khan Shinwari

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 182 citations in OpenAlex.

  1. Comparative study of niosomal nanoparticles encapsulatingInternational journal of reproductive biomedicine · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. RSC advances · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Rapid synthesis of highly monodisperse AgSbSBeilstein journal of nanotechnology · 2025
    Article
  16. Article
  17. Targeted therapy and biomarker-guided applications of ecofriendly silver nanoparticles in precision oncology.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ikram UllahDepartment of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan.ORCID https://orcid.org/0000-0002-7070-9053
Ali Talha KhalilDepartment of Pathology, Medical Technology Institution, Lady Reading Hospital, Peshawar, Pakistan.
Muhammad AliDepartment of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Javed IqbalDepartment of Plant Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Waqar AliDepartment of Biotechnology, University of Malakand, Chakdara, Lower Dir, Pakistan.
Saud AlarifiDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Zabta Khan ShinwariDepartment of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Quaid-i-Azam University · PKKing Saud University · SALady Reading Hospital · PKUniversity of Malakand · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver nanoparticles are among the most significant diagnostic and therapeutic agents in the field of nanomedicines. In the current study, the green chemistry approach was made to optimize a cost-effective synthesis protocol for silver nanoparticles from the aqueous extract of the important anticancer plant

Indexed as

ApoptosisBreast NeoplasmsCaspase 3Caspase 9Cell SurvivalFemaleGreen Chemistry TechnologyHumansMCF-7 CellsMetal NanoparticlesOxidative StressPlant ExtractsReactive Oxygen SpeciesSilverZygophyllaceaeCaspase 3Caspase 9Plant ExtractsReactive Oxygen SpeciesSilver

Identifiers

PMID33082906
PMCPMC7559220
OpenAlexW3092593061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.