Evidence map›Paper›PMID 33082841›Full record

ArticleComputational and mathematical methods in medicine2020

Effects of Single-Nucleotide Polymorphisms in Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2): A Comprehensive Study.

Zoya Khalid, Omar Almaghrabi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Zoya KhalidComputational Biology Research Lab, Department of Computer Science, National University of Computing and Emerging Sciences (NUCES-FAST), Islamabad, Pakistan.ORCID https://orcid.org/0000-0003-2075-462X
Omar AlmaghrabiDepartment of Biology, College of Science, University of Jeddah, Saudi Arabia.
National University of Computer and Emerging Sciences · PKUniversity of Jeddah · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calmodulin-dependent protein kinase kinase 2 (CAMKK2) is a protein kinase that belongs to the serine/threonine kinase family. It phosphorylates kinases like CAMK1, CAMK2, and AMP, and this signaling cascade is involved in various biological processes including cell proliferation, apoptosis, and proliferation. Also, the CAMKK2 signaling activity is required for the healthy activity of the brain which otherwise can cause diseases like bipolar disorders and anxiety. The current study is based on

Indexed as

Calcium-Calmodulin-Dependent Protein Kinase KinaseComputational BiologyComputer SimulationHumansMathematical ConceptsMolecular Docking SimulationMutation, MissensePolymorphism, Single NucleotideProtein ConformationProtein Interaction MapsSequence Homology, Amino AcidCalcium-Calmodulin-Dependent Protein Kinase KinaseCAMKK2 protein, human

Identifiers

PMID33082841
PMCPMC7559224
OpenAlexW3092505877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.