Evidence map›Paper›PMID 33082532›Full record

ArticleEye (London, England)2021

Brolucizumab-related retinal vasculitis: emerging disconnect between clinical trials and real world.

Ashish Sharma, Nilesh Kumar, Nikulaa Parachuri, Sonali Singh, Francesco Bandello, Baruch D Kuppermann, Anat Loewenstein

Registry-linked trialAbstract read
In one paragraph

Article in Eye (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05220085 (Real-life Beovu Experience at UZ Leuven for the Treatment of Exudative Neovascular Age-related Macular Degeneration), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05220085 unknown statusnot on this map

Real-life Beovu Experience at UZ Leuven for the Treatment of Exudative Neovascular Age-related Macular Degeneration

TypeobservationalSponsorUniversitaire Ziekenhuizen KU LeuvenRan2020 to 2022Enrolled17ConditionsAge-Related Macular DegenerationArmsBrolucizumab Ophthalmic Dbll 6 Mg/0.05 mL Intravitreal Solution
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Current landscape of drug induced retinal vasculitis.Journal of ophthalmic inflammation and infection · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Progress on the application of growth factor-related drugs in ophthalmology.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. [Acute unilateral loss of vision after intravitreal injection of a VEGF inhibitor].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2021
    Article
  13. Article
  14. Article
  15. Side Effects of Brolucizumab.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ashish SharmaLotus Eye Hospital and Institute, Avinashi Road, Coimbatore, TN, India. drashish79@hotmail.com.ORCID http://orcid.org/0000-0002-8550-9791
Nilesh KumarLotus Eye Hospital and Institute, Avinashi Road, Coimbatore, TN, India.ORCID http://orcid.org/0000-0002-7439-2081
Nikulaa ParachuriLotus Eye Hospital and Institute, Avinashi Road, Coimbatore, TN, India.
Sonali SinghMadhavi Netralaya, Ara, Bihar, India.
Francesco BandelloUniversity Vita-Salute, Scientific Institute San Raffaele, Milano, Italy.
Baruch D KuppermannGavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, USA.
Anat LoewensteinDivision of Ophthalmology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Retinal VasculitisAntibodies, Monoclonal, HumanizedHumansIntravitreal InjectionsAntibodies, Monoclonal, Humanizedbrolucizumab

Identifiers

PMID33082532
PMCPMC8182886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.