Evidence map›Paper›PMID 33082529›Full record

ArticleThe Journal of antibiotics2021

Antifungal activity and potential mechanism of magnoflorine against Trichophyton rubrum.

Nanxuan Luo, Liang Jin, Changqing Yang, Yurong Zhu, Xiaoli Ye, Xuegang Li, Baoshun Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Optimized Combinations of Filtrates ofJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. PeerJ · 2024
    Article
  4. Review:Open life sciences · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Isolation of coumarins with anti-Trichophyton rubrum activity from Heracleum vicinum Boiss.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  9. Review
  10. Potential Treatment of DermatophyteMolecules (Basel, Switzerland) · 2023
    Article
  11. Tinea pedis: an updated review.Drugs in context · 2023
    Review
  12. Review
  13. The Natural Alkaloid Tryptanthrin Induces Apoptosis-like Death inTropical medicine and infectious disease · 2022
    Article
  14. Article
  15. Article
  16. Isoflavaspidic Acid PB Extracted fromBioMed research international · 2022
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nanxuan Luo *College of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China.
Liang Jin *College of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China.
Changqing YangCollege of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China.
Yurong ZhuCollege of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China.
Xiaoli YeCollege of Life Science, Southwest University, 400716, Chongqing, PR China.
Xuegang LiCollege of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China. xuegangli@swu.edu.cn.
Baoshun ZhangCollege of Pharmaceutical Sciences, Southwest University, 400716, Chongqing, PR China. zbs360@swu.edu.cn.
Southwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coptis alkaloids show potent antifungal activity against Trichophyton rubrum (T. rubrum), which was a Tinea pedis fungus, but little of the literature was reported to investigate the antifungal activity of magnoflorine against it. Meanwhile, the potential mechanism of magnoflorine against T. rubrum is unknown. In the present study, we found that Coptis alkaloids, especially magnoflorine had significant antifungal activities against T. rubrum and Trichophyton mentagrophyte (T. mentagrophyte). The MIC values of magnoflorine against T. rubrum and T. mentagrophyte were both 62.5 μg ml

Indexed as

AlkaloidsAntifungal AgentsAporphinesArthrodermataceaeCoptisMicrobial Sensitivity TestsAlkaloidsAntifungal AgentsAporphinesmagnoflorine

Identifiers

PMID33082529
OpenAlexW3094272820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.