SynthesisScientific reports2020
Gastrointestinal symptoms and fecal nucleic acid testing of children with 2019 coronavirus disease: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Evidence linking COVID-19 and the health/well-being of children and adolescents: an umbrella review.BMC medicine · 2024Pooled it
- Viral shedding of SARS-CoV-2 in body fluids associated with sexual activity: a systematic review and meta-analysis.BMJ open · 2024Pooled it
- Gastrointestinal viral shedding in children with SARS-CoV-2: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2022Pooled it
- Frequency, dynamics, and duration of faecal shedding in SARS-CoV-2-infected individuals, a scoping review.Epidemiology and infection · 2026Article
- Long COVID and gut candidiasis: What is the existing relationship?World journal of gastroenterology · 2024Review
- Acute intestinal GVHD following donor-derived CD7-CAR-T-cell infusion in a child with Omicron COVID-19.Blood science (Baltimore, Md.) · 2023Article
- Evaluation of a Hospitalized Pediatric COVID-19 Cohort from Indian National Clinical Registry of COVID-19.Indian journal of pediatrics · 2023Article
- SARS-CoV-2 excretion kinetics in nasopharyngeal and stool samples from the pediatric population.Frontiers in medicine · 2023Article
- Intussusception and COVID-19 in Children: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2022Review
- The year 2021 in COVID-19 pandemic in children.Italian journal of pediatrics · 2022Review
- Article
- The Provision of Dental Care to COVID-19 Survivors: A Concise Review.International dental journal · 2022Review
- Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection.Med (New York, N.Y.) · 2022Article
- Isolated rhinorrhea in the presentation of SARS-CoV-2 infection among preschool- versus school-aged children.Paediatrics & child health · 2022Article
- Gastrointestinal, hepatic and pancreatic manifestations of COVID-19 in children.Clinics and research in hepatology and gastroenterology · 2022Review
- COVID-19 and Coinfections: A Serious Health Threat Requires Combination of Diagnosis and Therapy.Infectious disorders drug targets · 2022Article
- Coronavirus Disease 2019 (COVID-19) Lockdown: Morbidity, Perception, Behaviors, and Attitudes in French Families From the PARIS Birth Cohort.Frontiers in public health · 2022Article
- Gastrointestinal manifestations in children with COVID-19 infection: Retrospective tertiary center experience.Frontiers in pediatrics · 2022Article
- Transmission of severe acute respiratory syndrome coronavirus 2World journal of clinical cases · 2021Review
- Current systematic reviews and meta-analyses of COVID-19.World journal of virology · 2021Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to understand the clinical manifestations and incidence of gastrointestinal symptoms of coronavirus disease (COVID-19) in children and discuss the importance of fecal nucleic acid testing.We retrospectively analyzed studies on gastrointestinal symptoms and fecal nucleic acid detection in pediatric COVID-19 patients from January 1, 2020 to August 10, 2020, including prospective clinical studies and case reports. The results of fecal nucleic acid detection were analyzed systematically. Stata12.0 software was used for meta-analysis.The results showed that the most common gastrointestinal symptoms in children with COVID-19 were vomiting and diarrhea, with a total incidence of 17.7% (95% Cl 13.9-21.5%). However, the prevalence of gastrointestinal symptoms in other countries (21.1%, 95% CI 16.5-25.7%) was higher compared to China (12.9%, 95% CI 8-17.7%). In Wuhan, the pooled prevalence was much higher (41.3%, 95% CI 3.2-79.4%) compared to areas outside Wuhan in China (7.1%, 95% CI 4.0-10.3%). The positive rate of fecal nucleic acid testing in COVID-19 children was relatively high at 85.8% (91/106). Additionally, 71.2% (52/73) were still positive for fecal nucleic acid after respiratory tract specimens turned negative. One and two weeks after the respiratory tract specimens turned nucleic acid-negative, 45.2% (33/73) and 34.2% (25/73) patients, respectively, remained fecal nucleic acid-positive. The longest interval between the respiratory tract specimens turning negative and fecal specimens turning negative exceeded 70 days. Conclusions and relevance: gastrointestinal symptoms in pediatric COVID-19 are relatively common. Attention should be paid to the detection of fecal nucleic acids in children. Fecal nucleic acid-negative status should be considered as one of the desegregation standards.
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