ArticleScientific reports2020
B-box transcription factor 28 regulates flowering by interacting with constans.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Antagonistic regulation of PIF4 and HY5 activity by BBX28 regulates thermomorphogenesis.Science advances · 2026Article
- The CONSTANS-like gene family in wheat is involved in heading date and drought stress response.Scientific reports · 2025Article
- Seasonal changes in daily temperature fluctuation control flowering through a time-dependent regulation ofResearch square · 2025Article
- Exploring the multifaceted dynamics of flowering time regulation in field crops: Insight and intervention approaches.The plant genome · 2025Review
- The BBX family and their response to abiotic stress in ginger (Zingiber officinale Roscoe).BMC genomics · 2025Article
- Article
- Genome-Wide Identification of PeanutPlants (Basel, Switzerland) · 2024Article
- Identification of the CONSTANS-like family in Cymbidium sinense, and their functional characterization.BMC genomics · 2023Article
- Involvement of CONSTANS-like Proteins in Plant Flowering and Abiotic Stress Response.International journal of molecular sciences · 2023Review
- Regulation of Flowering Time by Environmental Factors in Plants.Plants (Basel, Switzerland) · 2023Review
- Genome-Wide Analysis of theInternational journal of molecular sciences · 2023Article
- Photoperiodic flowering in Arabidopsis: Multilayered regulatory mechanisms of CONSTANS and the florigen FLOWERING LOCUS T.Plant communications · 2023Review
- Multi-layered roles of BBX proteins in plant growth and development.Stress biology · 2023Review
- SlBBX28 positively regulates plant growth and flower number in an auxin-mediated manner in tomato.Plant molecular biology · 2022Article
- The sweet potato B-box transcription factor geneFrontiers in genetics · 2022Article
- AcBBX5, a B-box transcription factor from pineapple, regulates flowering time and floral organ development in plants.Frontiers in plant science · 2022Article
- Nuclear dynamics: Formation of bodies and trafficking in plant nuclei.Frontiers in plant science · 2022Review
- Genome-Wide Characterization and Anthocyanin-Related Expression Analysis of theFrontiers in genetics · 2022Article
- An Evolutionary Analysis of B-Box Transcription Factors in Strawberry Reveals the Role of FaBBx28c1 in the Regulation of Flowering Time.International journal of molecular sciences · 2021Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
B-box transcription factors (BBXs) are important regulators of flowering, photomorphogenesis, shade-avoidance, abiotic and biotic stresses and plant hormonal pathways. In Arabidopsis, 32 BBX proteins have been identified and classified into five groups based on their structural domains. Little is known about the fifth group members (BBX26-BBX32) and the detailed molecular mechanisms relevant to their functions. Here we identified B-box transcription factor 28 (BBX28) that interacts with Constans (CO), a transcriptional activator of Flowering Locus T (FT). Overexpressing BBX28 leads to late flowering with dramatically decreased FT transcription, and bbx28 deficient mutant displays a weak early flowering phenotype under long days (LD), indicating that BBX28 plays a negative and redundant role in flowering under LD. Additionally, the interaction between BBX28 and CO decreases the recruitment of CO to FT locus without affecting the transcriptional activation activity of CO. Moreover, the N-terminal cysteines, especially those within the B-box domain, are indispensable for the heterodimerization between BBX28 and CO and activation of CO on FT transcription. Genetic evidences show that the later flowering caused by BBX28 overexpression is compromised by CO ectopic expression. Collectively, these results supported that BBX28 functions with CO and FT to negatively regulate Arabidopsis flowering, in which the N-terminal conserved cysteines of BBX28 might play a central role.
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