Evidence map›Paper›PMID 33082240›Full record

ArticleMolecular cancer research : MCR2021

The Relative Expression of ERα Isoforms ERα66 and ERα36 Controls the Cellular Response to 24R,25-Dihydroxyvitamin D3 in Breast Cancer.

Anjali Verma, D Joshua Cohen, Thomas W Jacobs, Barbara D Boyan, Zvi Schwartz

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular cancer research : MCR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. 24R,25(OH)International journal of cancer · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anjali VermaDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia.
D Joshua CohenDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia.
Thomas W JacobsDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia.
Barbara D BoyanDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia. bboyan@vcu.edu.
Zvi SchwartzDepartment of Biomedical Engineering, Virginia Commonwealth University, Richmond, Virginia.
Georgia Institute of Technology · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Kim Felder Rhoads · 1985 to 2026
$51.0M
Mechanisms Mediating Osseointegration of 3D Printed Titanium ConstructsR01AR072500 · NIAMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI BOYAN, BARBARA D. · 2019 to 2023
$2.9M
NCI NIH HHS P30 CA016059NIAMS NIH HHS R01 AR072500
6 · The paper itself

Abstract

Vitamin D3 and its metabolites have antitumorigenic properties

Indexed as

AnimalsBreast NeoplasmsDisease Models, AnimalEstrogen Receptor alphaFemaleHumansMiceProtein IsoformsVitamin Ddihydroxy-vitamin D3ESR1 protein, humanEstrogen Receptor alphaProtein IsoformsVitamin D

Identifiers

PMID33082240
PMCPMC9250782
OpenAlexW3093981042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.