Evidence map›Paper›PMID 33082187›Full record

Trial reportBMJ open2020

Effects of external inspections on sepsis detection and treatment: a stepped-wedge study with cluster-level randomisation.

Gunnar Husabø, Roy Miodini Nilsen, Erik Solligård, Hans Kristian Flaatten, Kieran Walshe, Jan C Frich, Gunnar Tschudi Bondevik, Geir Sverre Braut, Jon Helgeland, Stig Harthug and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02747121 (Effects of External Inspection on Sepsis Detection and Treatment), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02747121 nacompletednot on this map

Effects of External Inspection on Sepsis Detection and Treatment

TypeinterventionalSponsorNorwegian Board of Health SupervisionRan2016 to 2020Enrolled7,407ConditionsSepsisArmsExternal inspection of health services
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gunnar HusabøDepartment of Social Science, Western Norway University of Applied Sciences, Sogndal, Norway.ORCID 0000-0002-8726-1769
Roy Miodini NilsenDepartment of Health and Functioning, Western Norway University of Applied Sciences, Bergen, Norway.
Erik SolligårdClinic of Anesthesia and Intensive Care, St. Olavs Hospital University Hospital in Trondheim, Trondheim, Norway.
Hans Kristian FlaattenDepartment of Clinical Medicine, University of Bergen, Bergen, Norway.
Kieran WalsheAlliance Manchester Business School, The University of Manchester, Manchester, UK.
Jan C FrichInstitute of Health and Society, University of Oslo, Oslo, Norway.
Gunnar Tschudi BondevikDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
Geir Sverre BrautDepartment of Research, Stavanger University Hospital, Stavanger, Norway.
Jon HelgelandNorwegian Institute of Public Health, Oslo, Norway.ORCID 0000-0002-9348-7844
Stig HarthugDepartment of Research and Development, Haukeland University Hospital, Bergen, Norway.
Einar HovlidDepartment of Social Science, Western Norway University of Applied Sciences, Sogndal, Norway einar.hovlid@hvl.no.ORCID 0000-0003-0300-4405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of external inspections on (1) hospital emergency departments' clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality.

designIncomplete cluster-randomised stepped-wedge design using data from patient records and patient registries. We compared care processes and patient outcomes before and after the intervention using regression analysis.

settingNationwide inspections of sepsis care in emergency departments in Norwegian hospitals.

participants7407 patients presenting to hospital emergency departments with sepsis.

interventionExternal inspections of sepsis detection and treatment led by a public supervisory institution.

main outcome measuresProcess measures for sepsis diagnostics and treatment, length of hospital stay and 30-day all-cause mortality.

resultsAfter the inspections, there were significant improvements in the proportions of patients examined by a physician within the time frame set in triage (OR 1.28, 95% CI 1.07 to 1.53), undergoing a complete set of vital measurements within 1 hour (OR 1.78, 95% CI 1.10 to 2.87), having lactate measured within 1 hour (OR 2.75, 95% CI 1.83 to 4.15), having an adequate observation regimen (OR 2.20, 95% CI 1.51 to 3.20) and receiving antibiotics within 1 hour (OR 2.16, 95% CI 1.83 to 2.55). There was also significant reduction in mortality and length of stay, but these findings were no longer significant when controlling for time.

conclusionsExternal inspections were associated with improvement of sepsis detection and treatment. These findings suggest that policy-makers and regulatory agencies should prioritise assessing the effects of their inspections and pay attention to the mechanisms by which the inspections might contribute to improve care for patients.

trial registrationNCT02747121.

Indexed as

SepsisEmergency Service, HospitalHumansLength of StayNorwayTriageaccident & emergency medicineauditchange managementhealth policyhealth & safetyinfectious diseases

Identifiers

PMID33082187
PMCPMC7577024

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.