ArticleCardiovascular diabetology2020
Global trend of diabetes mortality attributed to vascular complications, 2000-2016.
Article in Cardiovascular diabetology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06607497 (Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring), which is not on this map. Cited by 81 papers, 7 of them syntheses that pooled it.
What it found
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Better Risk Perception Via Patient Similarity to Control Hyperglycemia and Sustained by Telemonitoring
Who cites it
81 citing papers in PubMed, 7 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- The role of estimated glucose disposal rate in predicting cardiovascular risk among general and diabetes mellitus population: a systematic review and meta-analysis.BMC medicine · 2025Pooled it
- Sodium-Glucose Cotransporter 2 Inhibitors and Changes in Epicardial Adipose Tissue: A Systematic Literature Review And Meta-Analysis.Current vascular pharmacology · 2025Pooled it
- Influencing factors of stroke in patients with type 2 diabetes: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Unmasking the silent epidemic: a comprehensive systematic review and meta-analysis of undiagnosed diabetes in Ethiopian adults.Frontiers in endocrinology · 2024Pooled it
- Patient experiences of continuous glucose monitoring and sensor-augmented insulin pump therapy for diabetes: A systematic review of qualitative studies.Journal of diabetes · 2023Pooled it
- Economic Evaluation of Health Behavior Interventions to Prevent and Manage Type 2 Diabetes Mellitus in Asia: A Systematic Review of Randomized Controlled Trials.International journal of environmental research and public health · 2022Pooled it
- The efficacy and safety of dachaihu decoction in the treatment of type 2 diabetes mellitus: A systematic review and meta-analysis.Frontiers in pharmacology · 2022Pooled it
- Jinlida granules combined with metformin improved the standard-reaching rate of blood glucose and clinical symptoms of patients with type 2 diabetes: secondary analysis of a randomized controlled trial.Frontiers in endocrinology · 2023Trial
- Exploring the renoprotective potential of Beta vulgaris in diabetic nephropathy: an integrated network pharmacology, molecular docking and dynamics simulation study.Molecular diversity · 2026Article
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- Understanding the Relationship Between Weight Discrimination and Cardiometabolic Risk Factors in Diabetes: Findings from the English Longitudinal Study of Ageing (ELSA).International journal of behavioral medicine · 2026Article
- Tirzepatide Attenuates Wire Injury-Induced Arterial Remodeling in Non-Diabetic and Diabetic Mice: Comparison with Semaglutide.Biomedicines · 2026Article
- Coronary artery calcification in Type 2 diabetes mellitus: biochemical and inflammatory insights from the Pakistani Population - a case-control study.BMC endocrine disorders · 2026Article
- IDH2 deficiency enhances ferroptosis-induced vascular inflammation and remodeling in diabetes.Scientific reports · 2026Article
- The role of melatonin in attenuation of vascular endothelin-1 reactivity via calcium channels and endothelial derived relaxing factors in STZ-induced diabetic aortic rats.Journal of muscle research and cell motility · 2026Article
- Analysis and prediction of the trends in diabetes mellitus mortality in Chinese residents from 2008 to 2021.Archives of public health = Archives belges de sante publique · 2026Article
- FTO Gene rs9939609 is Potentially Associated with Diabetes Related Complications in T2DM Patients.Current diabetes reviews · 2026Article
- Gingerenone A attenuates diabetic vascular remodeling through AMPK/mTOR/S6K1 signaling.Frontiers in pharmacology · 2026Article
- Real-World Effectiveness and Safety of Imeglimin in Type 2 Diabetes: Prospective Multi-Center Study in Bangladesh.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe global epidemic of diabetes mellitus continues to grow and affects developed and developing countries alike. Intensive glycemic control is thought to modify the risks for vascular complications, hence the risks for diabetes-related death. We investigated the trend of diabetic vascular complication-related deaths between 2000 and 2016 in the global diabetes landscape.
methodsWe collected 17 years of death certificates data from 108 countries in the World Health Organization mortality database between 2000 and 2016, with coding for diabetic complications. Crude and age-standardized proportions and rates were calculated. Trend analysis was done with annual average percentage change (AAPC) of rates computed by joinpoint regression.
resultsFrom 2000 through 2016, 7,108,145 deaths of diabetes were reported in the 108 countries. Among them, 26.8% (1,904,787 cases) were attributed to vascular complications in damaged organs, including the kidneys (1,355,085 cases, 71.1%), peripheral circulatory (515,293 cases, 27.1%), nerves (28,697 cases, 1.5%) and eyes (5751 cases, 0.3%). Overall, the age-standardized proportion of vascular complication-related mortality was 267.8 [95% confidence interval (95% CI), 267.5-268.1] cases per 1000 deaths and the rate was 53.6 (95% CI 53.5-53.7) cases per 100,000 person-years. Throughout the 17-year period, the overall age-standardized proportions of deaths attributable to vascular complications had increased 37.9%, while the overall age-standardized mortality rates related to vascular complications had increased 30.8% (AAPC = 1.9% [1.4-2.4%, p < 0.05]). These increases were predominantly driven by a 159.8% increase in the rate (AAPC = 2.7% [1.2-4.3%, p < 0.05]) from renal complications. Trends in the rates and AAPC of deaths varied by type of diabetes and of complications, as well as by countries, regions and domestic income.
conclusionDiabetic vascular complication-related deaths had increased substantially during 2000-2016, mainly driven by the increased mortality of renal complications.
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