Evidence map›Paper›PMID 33081739›Full record

Trial reportBMC public health2020

Sankofa pediatric HIV disclosure intervention did not worsen depression scores in children living with HIV and their caregivers in Ghana.

Christopher Radcliffe, Aba Sam, Quinn Matos, Sampson Antwi, Kofi Amissah, Amina Alhassan, Irene Pokuaa Ofori, Yunshan Xu, Yanhong Deng, Nancy R Reynolds and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01701635 (A Bioecological Pediatric HIV Disclosure Intervention in Ghana - "SANKOFA"), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01701635 nacompletednot on this map

A Bioecological Pediatric HIV Disclosure Intervention in Ghana - "SANKOFA"

TypeinterventionalSponsorYale UniversityRan2013 to 2017Enrolled446ConditionsHIVArmsDisclosure intervention, usual care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Christopher RadcliffeDepartment of Pediatrics, Pharmacology & Public Health, Yale School of Medicine, 464 Congress Avenue, New Haven, CT, 06520, USA.
Aba SamDepartment of Pediatrics, Pharmacology & Public Health, Yale School of Medicine, 464 Congress Avenue, New Haven, CT, 06520, USA.
Quinn MatosDepartment of Pediatrics, Pharmacology & Public Health, Yale School of Medicine, 464 Congress Avenue, New Haven, CT, 06520, USA.
Sampson AntwiDepartment of Child Health, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology and Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Kofi AmissahDepartment of Child Health, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology and Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Amina AlhassanDepartment of Child Health, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology and Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Irene Pokuaa OforiDepartment of Child Health, School of Medicine and Dentistry, Kwame Nkrumah University of Science and Technology and Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Yunshan XuYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT, USA.
Yanhong DengYale Center for Analytical Sciences, Yale School of Public Health, New Haven, CT, USA.
Nancy R ReynoldsJohns Hopkins School of Nursing, Baltimore, MD, USA.
Elijah PaintsilDepartment of Pediatrics, Pharmacology & Public Health, Yale School of Medicine, 464 Congress Avenue, New Haven, CT, 06520, USA. elijah.paintsil@yale.edu.ORCID http://orcid.org/0000-0002-8283-4564
Sankofa Team
Komfo Anokye Teaching Hospital · GHYale University · USJohns Hopkins University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
A bioecological pediatric HIV disclosure intervention in Ghana - "SANKOFA"R01HD074253 · NICHD · YALE UNIVERSITY · PI PAINTSIL, ELIJAH, REYNOLDS, NANCY R · 2012 to 2016
$1.9M
Brown NIMHD Minority Health & Health Disparities International Research TrainingT37MD008655 · NIMHD · BROWN UNIVERSITY · PI FLANIGAN, TIMOTHY P · 2014 to 2018
$1.2M
NCATS NIH HHS UL1 TR001863NICHD NIH HHS R01 HD074253NIMHD NIH HHS T37 MD008655
6 · The paper itself

Abstract

backgroundThe 'Sankofa' pediatric HIV disclosure study (2013-2017) was an intervention that aimed to address the low prevalence of disclosure of HIV status in Ghana.

methodsWe conducted a cross-sectional study at the intervention site in Kumasi, Ghana, in 2019, (2 years after study closure) and administered the 21-item Beck Depression Inventory (BDI) and the 10-item Child Depression Inventory (CDI) to caregiver-child dyads who received the intervention.

resultsWe enrolled 65% (N = 157) of the original dyads in the present study. Between Sankofa enrollment baseline and the present study, both children and caregivers had significant (p < 0.0001) mean reductions in CDI scores and BDI scores, respectively. CDI scores of the children were significantly correlated with BDI scores of the caregivers (r = 0.019, p = 0.019). No statistically significant associations between disclosure status and either CDI score or BDI score were found.

conclusionsOur findings did not support caregivers' fears that disclosure leads to depression.

trial registrationClinicalTrials.gov Identifier: NCT01701635 (date of registration Oct 5, 2012).

Indexed as

DisclosureAdultCaregiversChildClinical Trials as TopicCross-Sectional StudiesDepressionFemaleGhanaHIV InfectionsHumansMaleMiddle AgedMinorsDepressionDisclosure interventionGhanaPediatric HIV

Identifiers

PMID33081739
PMCPMC7576749
OpenAlexW3093533982

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.