Evidence map›Paper›PMID 33081691›Full record

ArticleGenetics, selection, evolution : GSE2020

Genetic inbreeding depression load for morphological traits and defects in the Pura Raza Española horse.

Julia Poyato-Bonilla, Davinia I Perdomo-González, María J Sánchez-Guerrero, Luis Varona, Antonio Molina, Joaquim Casellas, Mercedes Valera

Open access · goldAbstract read
In one paragraph

Article in Genetics, selection, evolution : GSE, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 27 citations in OpenAlex.

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  10. The Social and Reproductive Challenges Faced by Free-Roaming Horse (Animals : an open access journal from MDPI · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Julia Poyato-BonillaDepartamento de Ciencias Agroforestales, ETSIA, Universidad de Sevilla, Ctra. Utrera km. 1, 41013, Sevilla, Spain.ORCID https://orcid.org/0000-0002-7287-5012
Davinia I Perdomo-GonzálezDepartamento de Ciencias Agroforestales, ETSIA, Universidad de Sevilla, Ctra. Utrera km. 1, 41013, Sevilla, Spain. davpergon1@alum.us.es.ORCID https://orcid.org/0000-0003-2618-105X
María J Sánchez-GuerreroDepartamento de Ciencias Agroforestales, ETSIA, Universidad de Sevilla, Ctra. Utrera km. 1, 41013, Sevilla, Spain.ORCID https://orcid.org/0000-0003-4357-9908
Luis VaronaDepartamento de Anatomía Embriología Y Genética Animal, Instituto Agroalimentario de Aragón (IA2), Universidad de Zaragoza, Zaragoza, 50013, Spain.ORCID https://orcid.org/0000-0001-6256-5478
Antonio MolinaDepartamento de Genética, Universidad de Córdoba, Córdoba, 14071, Spain.ORCID https://orcid.org/0000-0002-9566-6600
Joaquim CasellasDepartament de Ciència Animal I Dels Aliments, Universitat Autònoma de Barcelona, Bellaterra, 08193, Spain.ORCID https://orcid.org/0000-0002-4982-3556
Mercedes ValeraDepartamento de Ciencias Agroforestales, ETSIA, Universidad de Sevilla, Ctra. Utrera km. 1, 41013, Sevilla, Spain.ORCID https://orcid.org/0000-0003-1742-550X
Universidad de Sevilla · ESUniversidad de Zaragoza · ESUniversitat Autònoma de Barcelona · ESUniversity of Córdoba · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL-2017-84217-P
6 · The paper itself

Abstract

backgroundInbreeding is caused by mating between related individuals and is associated with reduced fitness and performance (inbreeding depression). Several studies have detected heterogeneity in inbreeding depression among founder individuals. Recently, a procedure was developed to predict hidden inbreeding depression load that is associated with founders using the Mendelian sampling of non-founders. The objectives of this study were to: (1) analyse the population structure and general inbreeding, and (2) test this recent approach for predicting hidden inbreeding depression load for four morphological traits and two morphology defects in the Pura Raza Española (PRE) horse breed.

resultsThe regression coefficients that were calculated between trait performances and inbreeding coefficients demonstrated the existence of inbreeding depression. In total, 58,772,533 partial inbreeding coefficients (F

conclusionsAlthough the average inbreeding depression loads presented negative values, a certain percentage of the animals showed neutral or even positive values. Thus, high levels of inbreeding do not always lead to a decrease in mean phenotypic value or an increase in morphological defects. Hence, individual inbreeding depression loads could be used as a tool to select the most appropriate breeding animals. The possibility of selecting horses that have a high genetic value and are more resistant to the deleterious effects of inbreeding should help improve selection outcomes.

Indexed as

Inbreeding DepressionQuantitative Trait, HeritableAnimalsGenetic FitnessGenetic LoadHorsesPedigree

Identifiers

PMID33081691
PMCPMC7576714
OpenAlexW3094551680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.