On a Magical Mystery Tour with 8-Bromo-Cyclic ADP-Ribose: From All-or-None Block to Nanojunctions and the Cell-Wide Web.

A Mark Evans

Open access · goldAbstract readReview

In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact, top 88% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

Raw defines a TIR-fold cADPR hydrolase cooperating with dSarm in development and axon degeneration.Cell communication and signaling : CCS · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

A Mark EvansCentre for Discovery Brain Sciences and Cardiovascular Science, Edinburgh Medical School, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, UK.

University of Edinburgh · GB

Funding

Biotechnology and Biological Sciences Research Council 01/A/S/07453British Heart Foundation FS/03/033/15432, FS/05/050, PG/05/128/19884, RG/12/14/29885, PG/10/95/28657British Heart Foundation PG/10/95/28657British Heart Foundation RG/12/14/29885Wellcome Trust WT046374 , WT056423, WT070772, WT074434, WT081195AIA, WT212923, WT093147

6 · The paper itself

Abstract

A plethora of cellular functions are controlled by calcium signals, that are greatly coordinated by calcium release from intracellular stores, the principal component of which is the sarco/endooplasmic reticulum (S/ER). In 1997 it was generally accepted that activation of various G protein-coupled receptors facilitated inositol-1,4,5-trisphosphate (IP

Indexed as

CalciumCalcium SignalingCyclic ADP-RiboseHumansInositol 1,4,5-Trisphosphate ReceptorsMyocytes, CardiacRyanodine Receptor Calcium Release Channel8-bromo-cyclic-ADP-riboseCalciumCyclic ADP-RiboseInositol 1,4,5-Trisphosphate ReceptorsRyanodine Receptor Calcium Release Channel8-bromo-cADPRarterial smooth musclecADPRcalciumhypoxic pulmonary vasoconstrictionKV7nanocoursenanojunctionnanospacenuclear invaginationnucleusryanodine receptorsarcoplasmic reticulumtwo pore channel 2

Identifiers

PMID33081414

DOI10.3390/molecules25204768

PMCPMC7587525

OpenAlexW3092996152

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.