Evidence map›Paper›PMID 33081400›Full record

ArticleCancers2020

Radiomic Features and Machine Learning for the Discrimination of Renal Tumor Histological Subtypes: A Pragmatic Study Using Clinical-Routine Computed Tomography.

Johannes Uhlig, Andreas Leha, Laura M Delonge, Anna-Maria Haack, Brian Shuch, Hyun S Kim, Felix Bremmer, Lutz Trojan, Joachim Lotz, Annemarie Uhlig

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Johannes UhligDepartment of Diagnostic and Interventional Radiology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.ORCID 0000-0003-3557-3194
Andreas LehaDepartment of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073 Goettingen, Germany.
Laura M DelongeDepartment of Diagnostic and Interventional Radiology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Anna-Maria HaackDepartment of Diagnostic and Interventional Radiology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Brian ShuchInstitute of Urologic Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.
Hyun S KimDepartment of Radiology and Biomedical Imaging, Division of Interventional Radiology, Yale School of Medicine, New Haven, CT 06510, USA.
Felix BremmerInstitute of Pathology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.ORCID 0000-0003-0367-6527
Lutz TrojanDepartment of Urology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Joachim LotzDepartment of Diagnostic and Interventional Radiology, University Medical Center Goettingen, Robert-Koch-Str. 40, 37075 Goettingen, Germany.
Annemarie UhligInstitute of Urologic Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Deutsche Gesellschaft für Urologie UhA1/FE-17NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

This study evaluates the diagnostic performance of radiomic features and machine learning algorithms for renal tumor subtype assessment in venous computed tomography (CT) studies from clinical routine. Patients undergoing surgical resection and histopathological assessment of renal tumors at a tertiary referral center between 2012 and 2019 were included. Preoperative venous-phase CTs from multiple referring imaging centers were segmented, and standardized radiomic features extracted. After preprocessing, class imbalance handling, and feature selection, machine learning algorithms were used to predict renal tumor subtypes using 10-fold cross validation, assessed as multiclass area under the curve (AUC). In total,

Indexed as

computed tomographycomputer-assistedimage interpretationmachine learningradiomicsrenal cell carcinoma

Identifiers

PMID33081400
PMCPMC7603020

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.