ReviewInternational journal of molecular sciences2020
Interactions of Gold and Silver Nanoparticles with Bacterial Biofilms: Molecular Interactions behind Inhibition and Resistance.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
124 citing papers in PubMed, 2 syntheses or guidelines pooled it, 289 citations in OpenAlex.
- Systematic review of silver and vanadium-based antibiofilm agents: mechanisms and efficacy in oral biofilms.Future microbiology · 2025Pooled it
- Effects of Metal and Metal Oxide Nanoparticles against Biofilm-Forming Bacteria: A Systematic Review.Journal of microbiology and biotechnology · 2024Pooled it
- Unlocking the potential of gold nanoparticles with insights into green synthesis, mechanisms, characterization and multifunctional applications.Discover nano · 2026Review
- Nanoparticles for autoimmune diseases: advancing diagnostics and therapeutic solutions.Acta pharmacologica Sinica · 2026Review
- Hybrid Sonochemical-Pressure Fabrication of tri-element nanohybrids for advanced biological protection in resin and metal dental crowns.Ultrasonics sonochemistry · 2026Article
- Nano-warfare in the oral cavity: antimicrobial strategies and mechanisms in nanodentistry.Odontology · 2026Review
- Silver-based N-heterocyclic carbene (NHC) complexes as emerging strategies against antimicrobial resistance.Archives of microbiology · 2026Review
- Biogenic Silver Nanoparticles Synthesised Using Staphylococcus saprophyticus Cell-Free Supernatant Exhibit Potent Antimicrobial Activities via Oxidative Stress.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Data-Driven Engineering of Antimicrobial Nanomaterials for Food Safety and Biomedical Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Phytogenic synthesis and characterization of silver nanoparticles from Crataegus songarica aqueous extract for comprehensive biological evaluation.Discover nano · 2026Article
- Chitosan-coated gold nanostars with photothermal activity for enhanced disinfection efficacy of sodium hypochlorite in antibacterial-based root canal therapy.BMC chemistry · 2026Article
- A Comprehensive Review on Various Mechanisms of Quorum Sensing Inhibition by Gold Nanoparticles.Current microbiology · 2026Review
- Cyclic Olefin Copolymer with a Noble Metal Nanostructures as an Antibacterial Material.International journal of molecular sciences · 2026Article
- Green nanotechnology: Adenanthera pavonina-derived silver nanoparticles with antibacterial and photocatalytic properties.Scientific reports · 2026Article
- Multiple virulence attenuating strategies against Pseudomonas aeruginosa: Natural, synthetic, and synergistic approaches.World journal of microbiology & biotechnology · 2026Review
- Antimicrobial nanomaterials in food packaging and preservation.RSC advances · 2026Review
- Nanomaterials as electrochemical regulators of bacterial biofilms through the modulation of extracellular electron transport and ion channels.Journal of nanobiotechnology · 2026Review
- Regulatory Mechanisms of Silver Nanoparticles on Seed Germination: A Multilevel Integrative Perspective.International journal of molecular sciences · 2026Review
- Eco-friendly nanoparticles fromNanoscale advances · 2026Article
- Ni-Fe Nanoparticles fromCurrent pharmaceutical design · 2026Article
64 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Many bacteria have the capability to form a three-dimensional, strongly adherent network called 'biofilm'. Biofilms provide adherence, resourcing nutrients and offer protection to bacterial cells. They are involved in pathogenesis, disease progression and resistance to almost all classical antibiotics. The need for new antimicrobial therapies has led to exploring applications of gold and silver nanoparticles against bacterial biofilms. These nanoparticles and their respective ions exert antimicrobial action by damaging the biofilm structure, biofilm components and hampering bacterial metabolism via various mechanisms. While exerting the antimicrobial activity, these nanoparticles approach the biofilm, penetrate it, migrate internally and interact with key components of biofilm such as polysaccharides, proteins, nucleic acids and lipids via electrostatic, hydrophobic, hydrogen-bonding, Van der Waals and ionic interactions. Few bacterial biofilms also show resistance to these nanoparticles through similar interactions. The nature of these interactions and overall antimicrobial effect depend on the physicochemical properties of biofilm and nanoparticles. Hence, study of these interactions and participating molecular players is of prime importance, with which one can modulate properties of nanoparticles to get maximal antibacterial effects against a wide spectrum of bacterial pathogens. This article provides a comprehensive review of research specifically directed to understand the molecular interactions of gold and silver nanoparticles with various bacterial biofilms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.