Evidence map›Paper›PMID 33081353›Full record

ArticleViruses2020

Diversity of tRNA Clusters in the Chloroviruses.

Garry A Duncan, David D Dunigan, James L Van Van Etten

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Genomic analysis ofVirus evolution · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Garry A DuncanNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583-0900, USA.
David D DuniganNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583-0900, USA.ORCID 0000-0001-9496-5396
James L Van Van EttenNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583-0900, USA.ORCID 0000-0002-5063-0049
University of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses rely on their host's translation machinery for the synthesis of their own proteins. Problems belie viral translation when the host has a codon usage bias (CUB) that is different from an infecting virus due to differences in the GC content between the host and virus genomes. Here, we examine the hypothesis that chloroviruses adapted to host CUB by acquisition and selection of tRNAs that at least partially favor their own CUB. The genomes of 41 chloroviruses comprising three clades, each infecting a different algal host, have been sequenced, assembled and annotated. All 41 viruses not only encode tRNAs, but their tRNA genes are located in clusters. While differences were observed between clades and even within clades, seven tRNA genes were common to all three clades of chloroviruses, including the tRNA

Indexed as

Codon UsageGenetic VariationGenome, ViralCodonCyanobacteriaHost Microbial InteractionsMultigene FamilyPhycodnaviridaePhylogenyRNA, TransferCodonRNA, Transferalgal viruseschlorovirusescodon usage bias (CUB)tRNA clusterstRNAs

Identifiers

PMID33081353
PMCPMC7589089
OpenAlexW3093136886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.