ArticleMaterials (Basel, Switzerland)2020
Heterogeneous Strain Distribution in the Subchondral Bone of Human Osteoarthritic Femoral Heads, Measured with Digital Volume Correlation.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- An overview of reliable and representative DVC measurements for musculoskeletal tissues.Journal of microscopy · 2025Review
- Freezing does not influence the microarchitectural parameters of the microstructure of the freshly harvested femoral head bone.Cell and tissue banking · 2024Article
- Microstructure of the human metastatic vertebral body.Frontiers in endocrinology · 2024Article
- A New Microarchitecture-Based Parameter to Predict the Micromechanical Properties of Bone Allografts.Materials (Basel, Switzerland) · 2023Article
- Bone metastases do not affect the measurement uncertainties of a global digital volume correlation algorithm.Frontiers in bioengineering and biotechnology · 2023Article
- Characterizing the Mechanical Behavior of Bone and Bone Surrogates in Compression Using pQCT.Materials (Basel, Switzerland) · 2022Article
- Digital volume correlation for the characterization of musculoskeletal tissues: Current challenges and future developments.Frontiers in bioengineering and biotechnology · 2022Review
- A novel specimen shape for measurement of linear strain fields by means of digital image correlation.Scientific reports · 2021Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
Osteoarthritis (OA) is a chronic disease, affecting approximately one third of people over the age of 45. Whilst the etiology and pathogenesis of the disease are still not well understood, mechanics play an important role in both the initiation and progression of osteoarthritis. In this study, we demonstrate the application of stepwise compression, combined with microCT imaging and digital volume correlation (DVC) to measure and evaluate full-field strain distributions within osteoarthritic femoral heads under uniaxial compression. A comprehensive analysis showed that the microstructural features inherent in OA bone did not affect the level of uncertainties associated with the applied methods. The results illustrate the localization of strains at the loading surface as well as in areas of low bone volume fraction and subchondral cysts. Trabecular thickness and connectivity density were identified as the only microstructural parameters with any association to the magnitude of local strain measured at apparent yield strain or the volume of bone exceeding yield strain. This work demonstrates a novel approach to evaluating the mechanical properties of the whole human femoral head in case of severe OA.
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