Evidence map›Paper›PMID 33081279›Full record

ArticleBiomedicines2020

Engineering and Preclinical Evaluation of Western Reserve Oncolytic Vaccinia Virus Expressing A167Y Mutant Herpes Simplex Virus Thymidine Kinase.

S M Bakhtiar Ul Islam, Young Mi Hong, Mefotse Saha Cyrelle Ornella, Daniel Ngabire, Hyunjung Jang, Euna Cho, Eung-Kyun Kim, Jessye Jin Joo Hale, Cy Hyun Kim, Soon Cheol Ahn and 2 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

S M Bakhtiar Ul IslamMedical Research Center, School of Medicine, Pusan National University, Yangsan 50612, Korea.ORCID 0000-0002-3335-3289
Young Mi HongLiver Center, Pusan National University Yangsan Hospital, Department of Internal Medicine, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Mefotse Saha Cyrelle OrnellaMedical Research Center, School of Medicine, Pusan National University, Yangsan 50612, Korea.ORCID 0000-0002-9597-0573
Daniel NgabireMedical Research Center, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Hyunjung JangMedical Research Center, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Euna ChoBionoxx Inc., Parkview Tower #1905, 248 Jeongjail-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13554, Korea.
Eung-Kyun KimBionoxx Inc., Parkview Tower #1905, 248 Jeongjail-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13554, Korea.
Jessye Jin Joo HaleBionoxx Inc., Parkview Tower #1905, 248 Jeongjail-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13554, Korea.
Cy Hyun KimBionoxx Inc., Parkview Tower #1905, 248 Jeongjail-ro, Bundang-gu, Seongnam-si, Gyeonggi-do 13554, Korea.
Soon Cheol AhnDepartment of Microbiology and Immunology, School of Medicine, Pusan National University, Yangsan, 50612, Korea.
Mong ChoLiver Center, Pusan National University Yangsan Hospital, Department of Internal Medicine, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Tae-Ho HwangMedical Research Center, School of Medicine, Pusan National University, Yangsan 50612, Korea.
Genome and Company (South Korea) · KRPusan National University · KRPusan National University Yangsan Hospital · KR

Funding

National R&D Program for Cancer Control, Ministry of Health and Welfare, Republic of Korea HA16C0013National Research Foundation of Korea (NRF) 741 grant, funded by the Korean government (MSIP) NRF-2015R1A5A2009656
6 · The paper itself

Abstract

Viral replication of

Indexed as

A167Yganciclovirherpes simplex virusoncolytic virusesthymidine kinasewestern reserve vaccinia virus

Identifiers

PMID33081279
PMCPMC7650665
OpenAlexW3093305142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.