Evidence map›Paper›PMID 33081054›Full record

ArticleCancers2020

Circulatory MIC-1 as a Determinant of Prostate Cancer Racial Disparity.

Dev Karan, Jo Wick, Seema Dubey, Ossama Tawfik, Peter Van Veldhuizen

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Dev KaranDepartment of Pathology, MCW Cancer Center and Prostate Cancer Center of Excellence, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
Jo WickDepartment of Biostatistics and Data Science, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Seema DubeyDepartment of Pathology, MCW Cancer Center and Prostate Cancer Center of Excellence, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.
Ossama TawfikDepartment of Pathology, Saint Luke's Health System of Kansas City, Kansas City, MO 64111, USA.
Peter Van VeldhuizenDepartment of Internal Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA.
Medical College of Wisconsin · USSaint Luke's Health System · USUniversity of Kansas Medical Center · USUniversity of Rochester Medical Center · US

Funding

Modulation of host intrinsic immunity to reduce prostate cancer disparityR01CA204786 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARAN, DEV · 2016 to 2021
$1.5M
Racial disparity of MIC-1 gene in prostate tumor biologyR21CA179733 · NCI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI KARAN, DEV · 2014 to 2015
$319k
NCI NIH HHS CA179733 and CA204786NCI NIH HHS R01 CA204786NCI NIH HHS R21 CA179733
6 · The paper itself

Abstract

In this study, we investigated the potential of MIC-1 (macrophage inhibitory cytokine-1) on the severity of prostate cancer between African American men and Caucasians. Differences between the races were examined using Mann-Whitney tests for continuous variables and Fisher's exact tests for categorical variables. Pearson's correlation coefficient was used to identify associations between continuous measures across all samples and within each race. Analysis of variance, including clinical parameters, was used to identify differences in serum and urine MIC-1 levels between races. We found significant differences between the two races for age (

Indexed as

biomarkerMIC-1prostate cancerracial disparity

Identifiers

PMID33081054
PMCPMC7603134
OpenAlexW3092767989

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.