Evidence map›Paper›PMID 33081030›Full record

ArticleInternational journal of environmental research and public health2020

Serum Calprotectin and Chemerin Concentrations as Markers of Low-Grade Inflammation in Prepubertal Children with Obesity.

Grażyna Rowicka, Hanna Dyląg, Magdalena Chełchowska, Halina Weker, Jadwiga Ambroszkiewicz

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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  10. Expression of adipokines in children with primary nephrotic syndrome and its association with hyperlipidemia.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Grażyna RowickaDepartment of Nutrition, Institute of Mother and Child, 01-211 Warsaw, Poland.
Hanna DylągDepartment of Nutrition, Institute of Mother and Child, 01-211 Warsaw, Poland.
Magdalena ChełchowskaDepartment of Screening Tests and Metabolic Diagnostics, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0002-6174-6813
Halina WekerDepartment of Nutrition, Institute of Mother and Child, 01-211 Warsaw, Poland.
Jadwiga AmbroszkiewiczDepartment of Screening Tests and Metabolic Diagnostics, Institute of Mother and Child, 01-211 Warsaw, Poland.ORCID 0000-0001-7320-7561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In adults, obesity is associated with chronic low-grade inflammation, which may cause long-term adverse health consequences. We evaluated whether obesity in prepubertal children also generates this kind of inflammation and whether calprotectin and chemerin may be useful markers for early detection of such inflammation in this group of children. The study population included 83 children aged 2 to 10 years; 62 with obesity and without components of metabolic syndrome and 21 healthy controls with normal body weight. White blood cell (WBC) count, concentrations of C-reactive protein (CRP), interleukin-6 (IL-6), calprotectin, and chemerin were determined in peripheral blood. Our study showed that in the group with obesity, serum concentrations of calprotectin and chemerin, as well as CRP were significantly higher as compared with the controls. We found a significant positive correlation between serum chemerin concentrations and BMI z-score (r = 0.33,

Indexed as

BiomarkersCase-Control StudiesChemokinesChildChild, PreschoolFemaleHumansInflammationIntercellular Signaling Peptides and ProteinsLeukocyte L1 Antigen ComplexMaleObesityPubertyBiomarkersChemokinesIntercellular Signaling Peptides and ProteinsLeukocyte L1 Antigen ComplexRARRES2 protein, humancalprotectinchemerinchronic low-grade inflammationobesityprepubertal children

Identifiers

PMID33081030
PMCPMC7589737
OpenAlexW3092742038

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.