Evidence map›Paper›PMID 33080949›Full record

ReviewCells2020

Pathways for Sensing and Responding to Hydrogen Peroxide at the Endoplasmic Reticulum.

Jennifer M Roscoe, Carolyn S Sevier

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
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  4. Redox signals and oxidative stress in the control of mitochondrial protein import.Protein science : a publication of the Protein Society · 2026
    Review
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  9. Article
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  11. Article
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  15. Making Universal Vaccines and Antibodies Through Glycoengineering.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  16. Pathogenic effects ofCurrent research in microbial sciences · 2025
    Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer M RoscoeDepartment of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-4506-3852
Carolyn S SevierDepartment of Molecular Medicine, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-3245-6988
Cornell University · US

Funding

Molecular mechanisms to maintain ER redox balanceR01GM105958 · NIGMS · CORNELL UNIVERSITY · PI SEVIER, CAROLYN S · 2014 to 2022
$2.9M
NIGMS NIH HHS R01 GM105958
6 · The paper itself

Abstract

The endoplasmic reticulum (ER) has emerged as a source of hydrogen peroxide (H

Indexed as

Signal TransductionAnimalsEndoplasmic ReticulumHumansHydrogen PeroxideModels, BiologicalMolecular ChaperonesHydrogen PeroxideMolecular ChaperonesBiPcysteine oxidationendoplasmic reticulum (ER)hydrogen peroxideIRE1reactive oxygen species (ROS)redox signalingSERCA2unfolded protein response (UPR)

Identifiers

PMID33080949
PMCPMC7603117
OpenAlexW3093050035

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.