Evidence map›Paper›PMID 33080863›Full record

ArticleBrain sciences2020

Effects of Combining High-Definition Transcranial Direct Current Stimulation with Short-Foot Exercise on Chronic Ankle Instability: A Pilot Randomized and Double-Blinded Study.

Yuanbo Ma, Keyi Yin, Wei Zhuang, Cui Zhang, Yong Jiang, Jin Huang, Brad Manor, Junhong Zhou, Yu Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Yuanbo MaSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Keyi YinSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.ORCID 0000-0002-9482-6190
Wei ZhuangSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Cui ZhangSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Yong JiangSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Jin HuangSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Brad ManorThe Hinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Boston, MA 02131, USA.
Junhong ZhouThe Hinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, Boston, MA 02131, USA.ORCID 0000-0002-7931-7646
Yu LiuSchool of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.
Shanghai University of Sport · CNHarvard University · US

Funding

National Key Research and Development Program of China 2018YFF0300500National Natural Science Foundation of China 81572213Shanghai University of Sport "Overseas Visiting Program" stfx20170102
6 · The paper itself

Abstract

(1) Background: Balance decline is highly prevalent in people suffering from chronic ankle instability (CAI). The control of balance depends upon multiple neurophysiologic systems including the activation of cortical brain regions (e.g., the primary sensorimotor cortex). The excitability of this region, however, is diminished in people with CAI. In this pilot double-blinded randomized controlled trial, we tested the effects of high-definition transcranial direct current stimulation (HD-tDCS) designed to facilitate the excitability of M1 and S1 in combination with short-foot exercise (SFE) training on proprioception and dynamic balance performance in individuals with CAI. (2) Methods: Thirty young adults completed baseline assessments including the Active Movement Extent Discrimination Apparatus (AMEDA), Joint Position Reproduction (JPR) test, Y-balance test, and the Sensory Organization Test (SOT). They were then randomized to receive a four-week intervention of SFE in combination with tDCS (i.e., HD-tDCS+SFE) or sham (i.e., control) stimulation. Baseline assessments were repeated once-weekly throughout the intervention and during a two-week follow-up period. (3) Results: Twenty-eight participants completed this study. Blinding procedures were successful and no adverse events were reported. As compared to the control group, the HD-tDCS+SFE group exhibited significant improvements in the JPR test, the Y balance test, and the SOT at different time points. No group by time interaction was observed in AMEDA test performance. (4) Conclusions: HD-tDCS combined with SFE may improve dynamic balance and proprioception in CAI. Larger, more definitive trials with extended follow-up are warranted.

Indexed as

dynamic balance functionhigh-definition transcranial direct current stimulationproprioceptionshort-foot exercise

Identifiers

PMID33080863
PMCPMC7602979
OpenAlexW3092684083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.