Evidence map›Paper›PMID 33080784›Full record

ArticleGenes2020

Point Mutations in the 14-α Sterol Demethylase Cyp51A or Cyp51C Could Contribute to Azole Resistance in

Jose Lucio, Irene Gonzalez-Jimenez, Olga Rivero-Menendez, Ana Alastruey-Izquierdo, Teresa Pelaez, Laura Alcazar-Fuoli, Emilia Mellado

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Expression Profiling and Molecular Modeling Analysis ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Contribution of the CYP51A Y119F Mutation to Azole Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Refractory versus resistant invasive aspergillosis.The Journal of antimicrobial chemotherapy · 2025
    Review
  8. Molecular Identification ofInfection and drug resistance · 2025
    Article
  9. Genomic Insights intoPathogens (Basel, Switzerland) · 2024
    Article
  10. Transcriptome Analysis ofMicroorganisms · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Recent advances in fungal xenobiotic metabolism: enzymes and applications.World journal of microbiology & biotechnology · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Journal of fungi (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jose LucioMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Irene Gonzalez-JimenezMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.ORCID 0000-0003-4821-4852
Olga Rivero-MenendezMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Ana Alastruey-IzquierdoMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.ORCID 0000-0001-8651-4405
Teresa PelaezHospital Universitario Central de Asturias, Fundación para la Investigación Biosanitaria del Principado de Asturias (FINBA), Oviedo, 33011 Asturias, Spain.
Laura Alcazar-FuoliMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.
Emilia MelladoMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Majadahonda, 28220 Madrid, Spain.ORCID 0000-0002-9801-0260
Instituto de Salud Carlos III · ESInstituto de Investigación Sanitaria del Principado de Asturias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by

Indexed as

Point MutationAntifungal AgentsAspergillus flavusAzolesCytochrome P-450 Enzyme SystemFungal ProteinsGene Expression Regulation, FungalAntifungal AgentsAzolescytochrome P-450 CYP51A, AspergillusCytochrome P-450 Enzyme SystemFungal ProteinsAspergillus flavusazole drugsazole resistance mechanismsCyp51sDMIs fungicides

Identifiers

PMID33080784
PMCPMC7602989
OpenAlexW3093242430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.