Evidence map›Paper›PMID 33080667›Full record

ArticleUltrasonography (Seoul, Korea)2021

Focal liver lesions: interobserver and intraobserver agreement of three-dimensional contrast-enhanced ultrasound-assisted volume measurements.

Tommaso Vincenzo Bartolotta, Antonio Sidoti Pinto, Roberto Cannella, Giorgia Porrello, Rossana Taravella, Angelo Randazzo, Adele Taibbi

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonography (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. New frontiers in liver ultrasound: From mono to multi parametricity.World journal of gastrointestinal oncology · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tommaso Vincenzo BartolottaSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Antonio Sidoti PintoSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Roberto CannellaSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Giorgia PorrelloSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Rossana TaravellaSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Angelo RandazzoSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Adele TaibbiSection of Radiology - BiND, University Hospital "Paolo Giaccone", Palermo, Italy.
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITFondazione Istituto G. Giglio di Cefalù · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study was conducted to assess the interobserver and intraobserver agreement of three-dimensional contrast-enhanced ultrasound (3D-CEUS) volume calculations of focal liver lesions (FLLs).

methodsThirty-nine patients (15 men and 24 women; mean age, 55.4 years) with 39 FLLs (mean size, 3.1±1.8 cm; size range, 1 to 8 cm) prospectively underwent 3D-CEUS. Four readers calculated the volume of each lesion in an independent and blinded fashion in two separate sessions by means of a semi-automatic, commercially available proprietary software. The differences in lesion volumes (cm3) among sessions and readers were assessed using the Mann-Whitney U test and the Kruskal-Wallis test. Bland-Altman analysis was also performed. Intraclass correlation coefficients (ICCs) with 95% confidence intervals (95% CIs) were calculated. The statistical significance level was set at P<0.05.

resultsAmong readers, there were no statistically significant differences in the first (P=0.953) and second (P=0.592) reading sessions for volume calculations of the 39 FLLs, with almost perfect inter-reader agreement (ICC values of the first reading session, 0.996; 95% CI, 0.992 to 0.998 and ICC value of the second reading session, 0.994; 95% CI, 0.990 to 0.997, respectively). For each of the four readers, there were no significant differences in volume calculations between the two sessions (P=0.503-0.924), and the intrareader agreement was almost perfect for each reader (R1: ICC, 0.995; 95% CI, 0.991 to 0.998; R2: ICC, 0.995; 95% CI, 0.988 to 0.997; R3: ICC, 0.996; 95% CI, 0.992 to 0.998; R4: ICC, 0.985; 95% CI, 0.971 to 0.992).

conclusion3D-CEUS volume calculations provided consistent measurements across different readers with almost perfect intrareader agreement.

Indexed as

3D ultrasoundContrast-enhanced ultrasonographyLiver diseasesTumor volume

Identifiers

PMID33080667
PMCPMC8217797
OpenAlexW3051899129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.