Evidence map›Paper›PMID 33080339›Full record

ReviewAlcohol (Fayetteville, N.Y.)2021

Alcohol use disorder: A pre-existing condition for COVID-19?

Kristina L Bailey, Derrick R Samuelson, Todd A Wyatt

Open access · hybridAbstract readReview
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Alcohol's Effects on the Lung and Lung Disease.Alcohol research : current reviews · 2025
    Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Breath and Bottle: Evaluating Pharmacotherapy for Alcohol Use Disorder on COPD Exacerbation Outcomes.International journal of chronic obstructive pulmonary disease · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Substances of abuse and their effect on SAR-CoV-2 pathogenesis.NeuroImmune pharmacology and therapeutics · 2023
    Review
  14. Article
  15. Article
  16. Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Review
  17. Article
  18. COVID-19: Reducing the risk via diet and lifestyle.Journal of integrative medicine · 2023
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kristina L BaileyResearch Service, Department of Veterans Affairs Omaha-Western Iowa Health Care System, Omaha, NE, 68105, United States; Pulmonary, Critical Care and Sleep, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 68198-5910, United States. Electronic address: kbailey@unmc.edu.
Derrick R SamuelsonPulmonary, Critical Care and Sleep, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 68198-5910, United States. Electronic address: derrick.samuelson@unmc.edu.
Todd A WyattResearch Service, Department of Veterans Affairs Omaha-Western Iowa Health Care System, Omaha, NE, 68105, United States; Pulmonary, Critical Care and Sleep, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 68198-5910, United States; Department of Environmental, Agricultural and Occupational Health, University of Nebraska Medical Center, Omaha, NE, 68198-5910, United States. Electronic address: twyatt@unmc.edu.
Nebraska Medical Center · USOmaha VA Medical Center · USUniversity of Nebraska Medical Center · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Surveillance of Agricultural Injuries in the Central States RegionsU54OH010162 · OH · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RAUTIAINEN, RISTO HEIKKI · 2011 to 2025
$23.6M
Mucociliary clearance in agingR01AG053553 · NIA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BAILEY, KRISTINA L · 2016 to 2020
$1.5M
Mechanisms by Which Alcohol-Induced Dysbiosis Impairs Host Defense Against Klebsiella PneumoniaeR00AA026336 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI SAMUELSON, DERRICK R · 2019 to 2021
$743k
Lung Innate COVID-19 Defense Specific to Veterans Risk CharacteristicsI01BX005413 · VA · OMAHA VA MEDICAL CENTER · PI BAILEY, KRISTINA L, WYATT, TODD A · 2021 to 2022
–
BLRD VA I01 BX003635BLRD VA I01 BX005413BLRD VA IK6 BX003781NIAAA NIH HHS R00 AA026336NIA NIH HHS R01 AG053553NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

Indexed as

AlcoholismAnimalsCOVID-19CytokinesEthanolHumansLungRisk FactorsCytokinesEthanolalcoholcoronavirusCOVID-19injurylungSARS-CoV-2

Identifiers

PMID33080339
PMCPMC7568767
OpenAlexW3093398814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.