ArticleAmerican journal of respiratory and critical care medicine2021
The Association of Aging Biomarkers, Interstitial Lung Abnormalities, and Mortality.
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 59 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.
- Proteomic Analysis of the Senescence-Associated Secretory Phenotype: GDF-15, IGFBP-2, and Cystatin-C Are Associated With Multiple Aging Traits.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Pooled it
- From ideal respiratory health to chronic lung disease: indicators of impaired respiratory health.Expert review of respiratory medicine · 2026Review
- Pulmonary fibrosis after COVID-19 is characterized by airway abnormalities and elevated club cell secretory protein-16.JCI insight · 2026Article
- Deep Learning-Based Estimated Pulmonary Biological Age From Chest Computed Tomography Images in Healthy Adults: Model Development and Validation Study.JMIR aging · 2026Article
- GDF15 participates in epithelial cell senescence in radiation-induced lung injury through the ERK1/2-p16 signaling pathway.PloS one · 2026Article
- Interstitial lung abnormalities: a mechanistic window into early fibrotic lung disease.Frontiers in medicine · 2026Review
- Pulmonary Disease in the Older Adult: A Review of Interstitial Lung Disease.Clinics in geriatric medicine · 2025Review
- Pharmacologic inhibition of IRE1α-dependent decay protects alveolar epithelial identity and prevents pulmonary fibrosis in mice.The Journal of clinical investigation · 2025Article
- Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases.Tuberculosis and respiratory diseases · 2025Article
- Interstitial Lung Abnormality in Health Screening Examinees: Prevalence, Outcomes, and Risk Factors.Journal of Korean medical science · 2025Article
- Review
- Proteomic Biomarkers of Survival in Non-Idiopathic Pulmonary Fibrosis Interstitial Lung Disease.American journal of respiratory and critical care medicine · 2025Article
- Protein biomarkers of interstitial lung abnormalities in relatives of patients with pulmonary fibrosis.The European respiratory journal · 2025Article
- Age-Associated Increase in Growth Differentiation Factor 15 Levels Correlates With Central Arterial Stiffness and Predicts All-Cause Mortality in a Sardinian Population Cohort.Journal of the American Heart Association · 2025Article
- Associations of albuminuria with interstitial lung abnormalities in older community-dwelling adults confounded by age.ERJ open research · 2025Article
- Clinical features of immune checkpoint inhibitor-related pneumonitis in older patients with lung cancer receiving immune checkpoint inhibitors-based therapy: a retrospective study.BMC geriatrics · 2025Article
- Krebs von den Lungen-6 as a biomarker for distinguishing between interstitial lung disease and interstitial lung abnormalities based on computed tomography findings.Journal of thoracic disease · 2025Article
- Current perspectives on interstitial lung abnormalities.The Korean journal of internal medicine · 2025Review
- Interstitial Lung Abnormalities: Unraveling the Journey from Incidental Discovery to Clinical Significance.Diagnostics (Basel, Switzerland) · 2025Review
- Prediction of pulmonary function decline in fibrous interstitial lung abnormalities based on quantitative chest CT parameters.BMC medical imaging · 2025Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
17 authors at 6 institutions in 2 countries.
Jason L SandersDivision of Pulmonary and Critical Care Medicine and.ORCID 0000-0002-6480-5436
Rachel K PutmanDivision of Pulmonary and Critical Care Medicine and.
Josée DupuisDepartment of Biostatistics, School of Public Health.
Hanfei XuDepartment of Biostatistics, School of Public Health.
Joanne M MurabitoDepartment of Medicine, and.
Tetsuro ArakiDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Mizuki NishinoDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Emelia J BenjaminDepartment of Medicine, and.
Daniel LevyDepartment of Medicine, and.ORCID 0000-0003-1843-8724
Vasan S RamachandranDepartment of Medicine, and.
George R WashkoDivision of Pulmonary and Critical Care Medicine and.
Jeffrey L CurtisDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-5191-4847
Christine M FreemanDivision of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, Michigan.
Russell P BowlerDepartment of Medicine, National Jewish Health-Health Sciences Center, University of Colorado at Denver, Denver, Colorado.
Hiroto HatabuDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
George T O'ConnorPulmonary Center, School of Medicine, Boston University, Boston, Massachusetts.
Gary M HunninghakeDivision of Pulmonary and Critical Care Medicine and.
Brigham and Women's Hospital · USFramingham Heart Study · USPulmonary and Critical Care Associates · USUniversity of Michigan · USBoston University · USNational Jewish Health · US
Funding
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8MFramingham Project/LevyZIAHL006001 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEVY, DANIEL · 2009 to 2025
$51.1MMetabolomic signatures of empysema and COPD progression in the COPDGene cohortR01HL089897 · NHLBI · NATIONAL JEWISH HEALTH · PI CRAPO, JAMES D · 2012 to 2016
$31.1MFRAMINGHAM HEART STUDY - YEAR 5 EXAM75N92019D00031 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN · 2019 to 2024
$29.8MThe American Lung Association (ALA) Lung Health CohortU01HL146408 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARNETHON, MERCEDES RENEE, KALHAN, RAVI · 2019 to 2024
$25.2MGenetic Epidemiology of COPDU01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2007 to 2021
$20.7MIDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M(2 of 2) Genetic Epidemiology of COPDR01HL089856 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI SILVERMAN, EDWIN K · 2012 to 2016
$18.9MConProject-006U54HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2018 to 2022
$18.8MRESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9MUnderstanding the Origins of Early COPDR01HL144718 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI CURTIS, JEFFREY LOUIS, HAN, MEILAN K · 2020 to 2024
$11.3MClinical Genetics and Screening for Pulmonary FibrosisR01HL130974 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI GARY MATTHEW HUNNINGHAKE, Benjamin Alexander Raby · 2016 to 2026
$10.0MCSRD VA I01 CX000911Intramural NIH HHS ZIA HL006001NCI NIH HHS R01 CA203636NHLBI NIH HHS 75N92019D00031NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001INHLBI NIH HHS K08 HL140087NHLBI NIH HHS N01 HC025195NHLBI NIH HHS R01 HL076784NHLBI NIH HHS R01 HL077477NHLBI NIH HHS R01 HL089856NHLBI NIH HHS R01 HL089897NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL111024NHLBI NIH HHS R01 HL122464NHLBI NIH HHS R01 HL130974NHLBI NIH HHS R01 HL135142NHLBI NIH HHS R01 HL137995NHLBI NIH HHS R01 HL141434NHLBI NIH HHS R01 HL144718NHLBI NIH HHS R21 HL140376NHLBI NIH HHS T32 HL007633NHLBI NIH HHS U01 HL089856NHLBI NIH HHS U01 HL146408NHLBI NIH HHS U54 HL120163NIA NIH HHS R01 AG028321NIA NIH HHS R01 AG031287NIA NIH HHS R01 AG067457NIH HHS OT2 OD026553
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdultAgedAge FactorsAgingBiomarkersFemaleGrowth Differentiation Factor 15HumansLongitudinal StudiesLung Diseases, InterstitialMaleMiddle AgedOdds RatioSurvival RateBiomarkersGDF15 protein, humanGrowth Differentiation Factor 15agingGDF15idiopathic pulmonary fibrosisinterstitial lung abnormalitiesmortality
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.