Evidence map›Paper›PMID 33080028›Full record

ArticleNucleic acids research2021

Peryton: a manual collection of experimentally supported microbe-disease associations.

Giorgos Skoufos, Filippos S Kardaras, Athanasios Alexiou, Ioannis Kavakiotis, Anastasia Lambropoulou, Vasiliki Kotsira, Spyros Tastsoglou, Artemis G Hatzigeorgiou

Abstract read
In one paragraph

Article in Nucleic acids research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
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  5. BGMDB: A curated database linking gut microbiota dysbiosis to brain disorders.Computational and structural biotechnology journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giorgos SkoufosDepartment of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.
Filippos S KardarasHellenic Pasteur Institute, Athens 11521, Greece.
Athanasios AlexiouHellenic Pasteur Institute, Athens 11521, Greece.
Ioannis KavakiotisDepartment of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.
Anastasia LambropoulouHellenic Pasteur Institute, Athens 11521, Greece.
Vasiliki KotsiraHellenic Pasteur Institute, Athens 11521, Greece.
Spyros TastsoglouDepartment of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.
Artemis G HatzigeorgiouDepartment of Electrical & Computer Engineering, Univ. of Thessaly, Volos 38221, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present Peryton (https://dianalab.e-ce.uth.gr/peryton/), a database of experimentally supported microbe-disease associations. Its first version constitutes a novel resource hosting more than 7900 entries linking 43 diseases with 1396 microorganisms. Peryton's content is exclusively sustained by manual curation of biomedical articles. Diseases and microorganisms are provided in a systematic, standardized manner using reference resources to create database dictionaries. Information about the experimental design, study cohorts and the applied high- or low-throughput techniques is meticulously annotated and catered to users. Several functionalities are provided to enhance user experience and enable ingenious use of Peryton. One or more microorganisms and/or diseases can be queried at the same time. Advanced filtering options and direct text-based filtering of results enable refinement of returned information and the conducting of tailored queries suitable to different research questions. Peryton also provides interactive visualizations to effectively capture different aspects of its content and results can be directly downloaded for local storage and downstream analyses. Peryton will serve as a valuable source, enabling scientists of microbe-related disease fields to form novel hypotheses but, equally importantly, to assist in cross-validation of findings.

Indexed as

Databases, FactualHost-Pathogen InteractionsBacterial InfectionsCohort StudiesData MiningGastrointestinal DiseasesHumansInternetMycosesNeoplasmsNeurodegenerative DiseasesResearch DesignSoftware

Identifiers

PMID33080028
PMCPMC7779029

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.