Evidence map›Paper›PMID 33079931›Full record

ArticlePloS one2020

Role of clinical, functional and social factors in the association between multimorbidity and quality of life: Findings from the Survey of Health, Ageing and Retirement in Europe (SHARE).

Tatjana T Makovski, Gwenaëlle Le Coroller, Polina Putrik, Yun Hee Choi, Maurice P Zeegers, Saverio Stranges, Maria Ruiz Castell, Laetitia Huiart, Marjan van den Akker

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05264207 (Nursing Students' Visits to Older Adults With Multiple Chronic Conditions), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05264207 nacompletednot on this mapstarted 2022, after this paper: background citation

Nursing Students' Visits to Older Adults With Multiple Chronic Conditions: Effects on Self-care and Other Related Variables (VISITAME)

TypeinterventionalSponsorUniversidad de AlmeriaRan2022 to 2023Enrolled252ConditionsChronic DiseaseArmsNursing students' home-visit programme, Standard care from Public Andalusian Health Service
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Lung function trajectory: a partial mediator of the relationships between depressive symptoms and health-related quality of life in the aging population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  17. Unmet Healthcare Needs Predict Depression Symptoms among Older Adults.International journal of environmental research and public health · 2022
    Article
  18. Review
  19. Article
  20. The Relationship between Income and Morbidity-Longitudinal Findings from the German Ageing Survey.International journal of environmental research and public health · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tatjana T MakovskiDepartment of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.ORCID 0000-0002-3334-4809
Gwenaëlle Le CorollerCompetence Centre for Methodology and Statistics, Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Polina PutrikDepartment of Health Services Research, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
Yun Hee ChoiDepartment of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.
Maurice P ZeegersChairgroup of Complex Genetics and Epidemiology, Nutrition and Metabolism in Translational Research, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.
Saverio StrangesDepartment of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Maria Ruiz CastellDepartment of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Laetitia HuiartDepartment of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.
Marjan van den AkkerDepartment of Family Medicine, Care and Public Health Research Institute, Maastricht University, Maastricht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAn increasing number of diseases is linked to deterioration of quality of life (QoL). Part of this association can be explained by socio-economic factors, which are most commonly accounted for. Our aim was to explore the potential contribution of other factors related to clinical burden, social interaction and functioning.

methodsA cross-sectional analysis was conducted on wave 6 of the population-based Survey of Health, Ageing and Retirement in Europe (SHARE), among participants aged 50+ (n = 67 179). The Control, Autonomy, Self-Realization and Pleasure (CASP-12v1) questionnaire measured QoL. The association between number of diseases and QoL was tested in a mixed-effects linear regression model. The base model controlled for socio-economic characteristics. Factors of interest (symptoms, polypharmacy, unmet care needs, utilisation of care, social network, personal and financial help, loneliness and activities of daily living (ADL) with instrumental activities (IADL)) were added to the base model one at a time and tested for relevance (i.e. change in the β-coefficient of the number of conditions of 15% or more).

resultsSymptoms, polypharmacy, loneliness and ADL/IADL appeared relevant and were retained in the final model. The association between number of conditions and QoL in the base model was -2.44 [95% CI: -2.72; -2.16], while this association was -0.76 [95%CI: -0.97; -0.54] after all relevant factors were included.

conclusionFactors beyond the socio-economic circumstances play an important role in explaining the association between number of conditions and QoL. These factors should be considered to better estimate the impact of chronic diseases on QoL, and for improving patient care.

Indexed as

MultimorbidityQuality of LifeActivities of Daily LivingAgedAged, 80 and overCross-Sectional StudiesEuropeFemaleHealth StatusHumansLonelinessMaleMiddle AgedPolypharmacySocial NetworkingSocial Support

Identifiers

PMID33079931
PMCPMC7575102

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.