ArticleGut microbes2020
Dietary cellulose induces anti-inflammatory immunity and transcriptional programs via maturation of the intestinal microbiota.
Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Gut microbiota bridges dietary nutrients and host immunity.Science China. Life sciences · 2023Pooled it
- Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults-A Double-Blind Trial.Molecular nutrition & food research · 2025Trial
- Nutraceutical blends predict enhanced health via microbiota reshaping improving cytokines and life quality: a Brazilian double-blind randomized trial.Scientific reports · 2024Trial
- The OMMGut microbes · 2026Review
- The association between dietary protein and gallstones in adults under 60 years old: A cross-sectional study.Medicine · 2026Article
- Aging-related decline in the liver and brain is accelerated by refined diet consumption.GeroScience · 2026Article
- A comprehensive review on structural, chemical, and functional perspectives of dietary polysaccharide-driven gut microbiota modulation: Mechanisms and challenges.Biochemistry and biophysics reports · 2026Review
- Effect of a Combination of Prebiotic Supplements Based on Fucus and Kelp on the Gut Microbiome of Mice with Induced Inflammation.Microorganisms · 2026Article
- Investigating the Role of Diet-Manipulated Gut Bacteria in Pathogenesis of Type 2 Diabetes Mellitus-AnNutrients · 2026Article
- Fiber mixtures containing chicory inulin, wheat dextrin, and cellulose, or tapioca dextrin alone, beneficially modulate microbial metabolic activity and composition in short-term colonic simulations.Frontiers in nutrition · 2026Article
- Gut microbiota-derived metabolites and IL-22 signaling in inflammatory bowel disease: context-dependent regulation of mucosal repair and inflammation.Frontiers in immunology · 2026Review
- REG/Reg family proteins: mediating gut microbiota homeostasis and implications in digestive diseases.Gut microbes · 2025Review
- Fiber enrichment is not superior to dietary monitoring in MASLD: A dual-center, double-blind, placebo-controlled trial.iScience · 2025Article
- Long-term follow-up study on the impact of a gut microbiota-supportive diet on heart failure and mortality outcomes.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Association between plant dietary fiber intake and hyperuricemia risk in Chinese children aged 6-17 years.Asia Pacific journal of clinical nutrition · 2025Article
- Mechanistic insights into microbiome-dependent and personalized responses to dietary fibre in a randomized controlled trial.medRxiv : the preprint server for health sciences · 2025Article
- Artificial cellulose derivatives are metabolized by select human gut Bacteroidota upon priming with common plant β-glucans.Journal of bacteriology · 2025Article
- Impact of Dietary Fiber on Inflammation in Humans.International journal of molecular sciences · 2025Review
- Article
- Bioactive Hydrogel Formulation Based on Ferulic Acid-Grafted Nano-Chitosan and Bacterial Nanocellulose Enriched with Selenium Nanoparticles from Kombucha Fermentation.Journal of functional biomaterials · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is generally accepted that dietary fiber is health promoting, the underlying immunological and molecular mechanisms are not well defined, especially with respect to cellulose, the most ubiquitous dietary fiber. Here, the impact of dietary cellulose on intestinal microbiota, immune responses and gene expression in health and disease was examined. Lack of dietary cellulose disrupted the age-related diversification of the intestinal microbiota, which subsequently remained in an immature state. Interestingly, one of the most affected microbial genera was
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.