Evidence map›Paper›PMID 33079311›Full record

ArticleInternational ophthalmology2021

Macular capillary system and ganglion cell-layer complex of the amblyopic eye with optical cohorence tomography angiography and optical cohorence tomography.

F G Yilmaz Cinar, G Ozkan

Abstract read
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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  11. Evaluation of optical coherence tomography findings according to treatment response in patients with amblyopia.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

F G Yilmaz CinarSaglik Bakanligi Ankara Egitim ve Arastirma Hastanesi Altındag, Ankara, Turkey. gycinar@gmail.com.ORCID http://orcid.org/0000-0001-8158-173X
G OzkanSaglik Bakanligi Ankara Egitim ve Arastirma Hastanesi Altındag, Ankara, Turkey.
Ankara Atatürk Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the macular capillary system and ganglion cell-layer complex of the amblyopic eye with OCTA and OCT in comparison with fellow non-amblyopic eyes and a healthy control group and to examine their relationship with the severity of amblyopia.

methodsThis prospective, cross-sectional comparative study enrolled 25 amblyopic patients and 25 healthy controls. All patients and controls underwent OCTA and OCT imagining. Macular vessel densities of the Superficial Capillary Plexus (SCP) and Deep Capillary Plexus (DCP) and retinal thickness were measured by OCTA and ganglion cell layer (GCL) by OCT.

resultsSCP density at the fovea and parafovea was significantly lower in amblyopic eyes than in fellow eyes and control group. DCP density at the fovea was significantly lower in amblyopic eyes than fellow eyes and control group. Mean GCL thickness on OCT was 0.73 ± 0.07 μm in amblyopic eyes, 0.75 ± 0.06 μm in fellow eyes and 0.77 ± 0.06 μm in the control group. GCL volume was significantly lower in amblyopic eyes than the fellow eyes. The SCP and DCP and GCL thickness were not affected by the severity of amblyopia.

conclusionMacular vessel densities of the SCP and DCP of eyes with amblyopia is lower compared to the fellow non-amblyopic eyes and the control group. The thickness of GCL was lower in amblyopic eyes than fellow eyes while the severity of amblyopia did not have any impact on these structures. Microvascular retinal structures may have been affected in the course of amblyopia development.

Indexed as

AmblyopiaAngiographyCross-Sectional StudiesFluorescein AngiographyHumansProspective StudiesRetinal VesselsTomography, Optical CoherenceVisual AcuityAmblyopiaGanglion cell-layer complexMacular capillary systemOptical cohorence tomographyOptical cohorence tomography angiography

Identifiers

PMID33079311
OpenAlexW3093190318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.