Evidence map›Paper›PMID 33079061›Full record

ArticleeLife2020

Conditional protein tagging methods reveal highly specific subcellular distribution of ion channels in motion-sensing neurons.

Sandra Fendl, Renee Marie Vieira, Alexander Borst

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 49 citations in OpenAlex.

  1. Distribution and voltage dependence of ion channels shape single-neuron computations.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  7. FETCH enables fluorescent labeling of membrane proteins in vivo with spatiotemporal control inProceedings of the National Academy of Sciences of the United States of America · 2025
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  9. Molecular organization of central cholinergic synapses.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  11. Constitutive and Conditional Epitope Tagging of Endogenous G-Protein-Coupled Receptors inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
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  13. Biased cell adhesion organizes a circuit for visual motion integration.bioRxiv : the preprint server for biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sandra Fendl *Max Planck Institute of Neurobiology, Martinsried, Germany.ORCID 0000-0001-6442-2542
Renee Marie Vieira *Max Planck Institute of Neurobiology, Martinsried, Germany.ORCID 0000-0001-8520-7382
Alexander BorstMax Planck Institute of Neurobiology, Martinsried, Germany.
Max Planck Institute of Neurobiology · DE

Funding

DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
NIH HHS P40 OD010949
6 · The paper itself

Abstract

Neurotransmitter receptors and ion channels shape the biophysical properties of neurons, from the sign of the response mediated by neurotransmitter receptors to the dynamics shaped by voltage-gated ion channels. Therefore, knowing the localizations and types of receptors and channels present in neurons is fundamental to our understanding of neural computation. Here, we developed two approaches to visualize the subcellular localization of specific proteins in

Indexed as

AnimalsDrosophila melanogasterIon ChannelsMotion PerceptionOptic Lobe, NonmammalianReceptors, CholinergicReceptors, GABAReceptors, GlutamateSensory Receptor CellsIon ChannelsReceptors, CholinergicReceptors, GABAReceptors, Glutamatechromosomesconditional labelingD. melanogasterFlpTaggene expressionmotion visionneuroscienceprotein labelingT4/T5 neurons

Identifiers

PMID33079061
PMCPMC7655108
OpenAlexW3092750717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.