Evidence map›Paper›PMID 33079035›Full record

ArticleEmerging infectious diseases2020

High Dengue Burden and Circulation of 4 Virus Serotypes among Children with Undifferentiated Fever, Kenya, 2014-2017.

Melisa M Shah, Bryson A Ndenga, Francis M Mutuku, David M Vu, Elysse N Grossi-Soyster, Victoria Okuta, Charles O Ronga, Philip K Chebii, Priscilla Maina, Zainab Jembe and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 5 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. Vector competence acrossJournal of virology · 2026
    Review
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  15. Temporal Variation and Human Host Predominance inPathogens (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 3 countries.

Melisa M Shah
Bryson A Ndenga
Francis M Mutuku
David M Vu
Elysse N Grossi-Soyster
Victoria Okuta
Charles O Ronga
Philip K Chebii
Priscilla Maina
Zainab Jembe
Carren M Bosire
Jael S Amugongo
Malaya K Sahoo
ChunHong Huang
Jenna Weber
Sean V Edgerton
Jimmy Hortion
Shannon N Bennett
Benjamin A Pinsky
A Desiree LaBeaud
École Normale Supérieure - PSL · FRÉcole Normale Supérieure de Lyon · FRKenya Medical Research Institute · KEStanford University · USTechnical University of Mombasa · KECalifornia Academy of Sciences · US

Funding

The child health impacts of overlapping vector-borne diseases in KenyaR01AI102918 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud · 2013 to 2026
$7.7M
Global Epidemiology of Infectious DiseasesT32AI052073 · NIAID · STANFORD UNIVERSITY · PI Angelle Desiree LaBeaud, Stephen Patrick Luby · 2003 to 2026
$4.2M
NIAID NIH HHS R01 AI102918NIAID NIH HHS T32 AI052073
6 · The paper itself

Abstract

Little is known about the extent and serotypes of dengue viruses circulating in Africa. We evaluated the presence of dengue viremia during 4 years of surveillance (2014-2017) among children with febrile illness in Kenya. Acutely ill febrile children were recruited from 4 clinical sites in western and coastal Kenya, and 1,022 participant samples were tested by using a highly sensitive real-time reverse transcription PCR. A complete case analysis with genomic sequencing and phylogenetic analyses was conducted to characterize the presence of dengue viremia among participants during 2014-2017. Dengue viremia was detected in 41.9% (361/862) of outpatient children who had undifferentiated febrile illness in Kenya. Of children with confirmed dengue viremia, 51.5% (150/291) had malaria parasitemia. All 4 dengue virus serotypes were detected, and phylogenetic analyses showed several viruses from novel lineages. Our results suggests high levels of dengue virus infection among children with undifferentiated febrile illness in Kenya.

Indexed as

DengueDengue VirusChildChild, PreschoolCost of IllnessFeverHumansKenyaPhylogenySerogrouparboviruseschildrencirculationdenguedengue virusdisease burdenKenyaserotypesundifferentiated feverviruseszoonoses

Identifiers

PMID33079035
PMCPMC7588514
OpenAlexW3092696616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.