Evidence map›Paper›PMID 33078441›Full record

Observational studyNutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition2020

Utility of Mid-Upper Arm Circumference in Diagnosing Malnutrition in Children With Cystic Fibrosis.

Rachel Y Phong, Sandra L Taylor, Brandt A Robinson, Sanjay Jhawar, Kiran Nandalike

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Update on Cystic Fibrosis in Pediatric Patients.Current gastroenterology reports · 2023
    Review
  6. Review
  7. Article
  8. Quality of anthropometric data measured in children and adolescents with cystic fibrosis: a scoping review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Rachel Y PhongDepartment of Food and Nutrition Services, University of California Davis Health, Sacramento, California, USA.
Sandra L TaylorDivision of Biostatistics, Department of Public Health Sciences, University of California Davis, Sacramento, California, USA.
Brandt A RobinsonDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of California Davis Health, Sacramento, California, USA.
Sanjay JhawarDivision of Pulmonary Medicine, Department of Pediatrics, University of California Davis Health, Sacramento, California, USA.
Kiran NandalikeDivision of Pulmonary Medicine, Department of Pediatrics, University of California Davis Health, Sacramento, California, USA.ORCID https://orcid.org/0000-0002-0176-5617
University of California Davis Medical Center · USCalifornia Department of Food and Agriculture · USUniversity of California, Davis · USUniversity of California System · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
NCATS NIH HHS UL1 TR001860
6 · The paper itself

Abstract

backgroundStandardized diagnostic indicators for malnutrition using growth percentile z-scores (weight for length or body mass index [BMI]) and mid-upper arm circumference (MUAC) z-scores are being used in clinical practice; however, their application to the pediatric cystic fibrosis (CF) population is not well described. In this study, we aim to compare growth percentile z-scores and MUAC z-scores in diagnosing and classifying malnutrition in children with CF and assess the relationship between their degree of malnourishment and corresponding pulmonary function tests (PFTs).

methodsIn this retrospective observational outpatient study of 49 pediatric CF patients, data were collected on baseline characteristics, anthropometrics, and PFTs over 12 months. Agreement in malnutrition diagnoses was quantified by Cohen κ statistics. Pearson test assessed the correlation between MUAC and BMI z-scores as well as PFTs and anthropometrics. Serial anthropometrics and PFTs were obtained and compared for a subset of patients (n = 28).

resultsGrowth percentile and MUAC z-scores were positively correlated in diagnosing malnutrition (Pearson correlation r = 0.87), but MUAC z-scores identified more patients as malnourished compared with growth percentile z-scores (49% vs 12%, Cohen κ of 0.22 [95% CI, 0.04-0.40]). There was no significant relationship between anthropometrics and PFTs. MUAC z-scores increased significantly over time, but BMI z-scores did not show this trend.

conclusionsOur small-scale data suggest a promising role for MUAC z-scores in classifying malnutrition and in measuring changes in nutrition status over time in pediatric CF.

Indexed as

Child Nutrition DisordersCystic FibrosisMalnutritionAdolescentAnthropometryArmBody WeightChildChild, PreschoolFemaleHumansMaleRetrospective Studiesarm circumferencebody mass indexcystic fibrosisgrowthmalnutritionpediatricspulmonary function tests

Identifiers

PMID33078441
PMCPMC7688066
OpenAlexW3093232617

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.