Evidence map›Paper›PMID 33078367›Full record

Observational studyAnnals of biomedical engineering2020

Effects of the Lower Airway Secretions on Airway Opening Pressures and Suction Pressures in Critically Ill COVID-19 Patients: A Computational Simulation.

Zhenglong Chen, Ming Zhong, Li Jiang, Nanshan Chen, Shengjin Tu, Yuan Wei, Ling Sang, Xia Zheng, Chunyuan Zhang, Jiale Tao and 2 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Publications About COVID-19 Research by the BME Community.Annals of biomedical engineering · 2022
    Article
  5. Hypoxaemia in the early stage of COVID-19: prevalence of physical or biochemical factors?European respiratory review : an official journal of the European Respiratory Society · 2022
    Article
  6. Review
  7. Ventilation/perfusion mismatch is not the sole reason for hypoxaemia in early stage COVID-19 patients.European respiratory review : an official journal of the European Respiratory Society · 2022
    Article
  8. Ex-vivo mucolytic and anti-inflammatory activity of BromAc in tracheal aspirates from COVID-19.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Zhenglong ChenSchool of Medical Instrumentation, Shanghai University of Medicine & Health Sciences, 257 Tianxiong Road, Shanghai, 201318, China.ORCID http://orcid.org/0000-0002-4075-251X
Ming ZhongDepartment of Intensive Care Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China. zhong_ming@fudan.edu.cn.
Li JiangDepartment of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, 100053, China.
Nanshan ChenDepartment of Respiratory and Critical Care Medicine, Wuhan Jinyintan Hospital, 1 Yintan Road, Dongxihu District, Wuhan, 430023, China.
Shengjin TuDepartment of Respiratory and Critical Care Medicine, Wuhan Jinyintan Hospital, 1 Yintan Road, Dongxihu District, Wuhan, 430023, China.
Yuan WeiDepartment of Respiratory and Critical Care Medicine, Wuhan Jinyintan Hospital, 1 Yintan Road, Dongxihu District, Wuhan, 430023, China.
Ling SangDepartment of Critical Care Medicine, GuangZhou Institute of Respiratory Health, The First Affiliated Hospital of GuangZhou Medical University, 151 Yanjiangxi Road, Guangzhou, 510120, China.
Xia ZhengDepartment of Critical Care Medicine, The First Affiliated Hospital of Zhejiang University, Hangzhou, 310003, Zhejiang, China.
Chunyuan ZhangNMPA Key Laboratory for Respiratory and Anaesthetic Equipment, 1 Jinyinhua Road, Shanghai, 201321, China.
Jiale TaoDepartment of Intensive Care Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Linhong DengChangzhou Key Laboratory of Respiratory Medical Engineering, Institute of Biomedical Engineering and Health Sciences, Changzhou University, Changzhou, 213164, Jiangsu, China.
Yuanlin SongDepartment of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Xuhui District, Shanghai, 200032, China.
Fudan University · CNJinyintan Hospital · CNCapital Medical University · CNChangzhou University · CNFirst Affiliated Hospital of Guangzhou Medical University · CNFirst Affiliated Hospital Zhejiang University · CNNational Medical Products Administration · CNShanghai University of Medicine and Health Sciences · CN

Funding

National Natural Science Foundation of China 11532003National Natural Science Foundation of China 31670950National Natural Science Foundation of China 81971807National Natural Science Foundation of China 82041003
6 · The paper itself

Abstract

In patients with critically ill COVID-19 pneumonia, lower airways are filled with plenty of highly viscous exudates or mucus, leading to airway occlusion. The estimation of airway opening pressures and effective mucus clearance are therefore two issues that clinicians are most concerned about during mechanical ventilation. In this study we retrospectively analyzed respiratory data from 24 critically ill patients with COVID-19 who received invasive mechanical ventilation and recruitment maneuver at Jinyintan Hospital in Wuhan, China. Among 24 patients, the mean inspiratory plateau pressure was 52.4 ± 4.4 cmH

Indexed as

Computer SimulationModels, BiologicalPulmonary Gas ExchangeRespiratory MechanicsSARS-CoV-2AdultAgedAir PressureCOVID-19Critical IllnessFemaleHumansLungMaleMiddle AgedRetrospective StudiesAirway mucusAirway opening pressureCoronavirus disease 2019Endotracheal suctioningRespiratory mechanics

Identifiers

PMID33078367
PMCPMC7571532
OpenAlexW3089810292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.