Evidence map›Paper›PMID 33078327›Full record

ReviewNeurosurgical review2021

Biomarkers for traumatic brain injury: a short review.

Marcela Usberti Gutierre, João Paulo Mota Telles, Leonardo Christiaan Welling, Nícollas Nunes Rabelo, Manoel Jacobsen Teixeira, Eberval Gadelha Figueiredo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcela Usberti GutierreDivision of Neurosurgery, University of São Paulo, São Paulo, Brazil.
João Paulo Mota TellesDivision of Neurosurgery, University of São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0001-9322-0405
Leonardo Christiaan WellingDepartment of Neurological Surgery, State University of Ponta Grossa, Ponta Grossa, Brazil.
Nícollas Nunes RabeloDivision of Neurosurgery, University of São Paulo, São Paulo, Brazil.
Manoel Jacobsen TeixeiraDivision of Neurosurgery, University of São Paulo, São Paulo, Brazil.
Eberval Gadelha FigueiredoDivision of Neurosurgery, University of São Paulo, São Paulo, Brazil. ebgadelha@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cellular response to TBI is a mixture of excitotoxicity, neuroinflammation, and cell death. Biomarkers that can track these lesions and inflammatory processes are being explored for their potential to provide objective measures in the evaluation of TBI, from prehospital care to rehabilitation. By understanding the pathways involved, we could be able to improve diagnostic accuracy, guide management, and prevent long-term disability. We listed some of the recent advances in this translational, intriguing, fast-growing field. Although the knowledge gaps are still significant, some markers are showing promising results and could be helping patients in the near future.

Indexed as

Brain Injuries, TraumaticBiomarkersHumansBiomarkersBiomarkersInflammationPrognosisTraumatic brain injury

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.