Evidence map›Paper›PMID 33078217›Full record

ArticleWorld journal of surgery2021

Papillary Thyroid Carcinoma in Children: Clinicopathological Profile and Outcomes of Management.

John K Thomas, Jujju Jacob Kurian, Anish Jacob Cherian, Julie Hephzibah, M J Paul, Deepak Thomas Abraham

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Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John K ThomasDept of Pediatric Surgery, Christian Medical College, Vellore, India.
Jujju Jacob KurianDept of Pediatric Surgery, Christian Medical College, Vellore, India.
Anish Jacob CherianDept of Endocrine Surgery, Christian Medical College and Hospital, Vellore, India. anish@cmcvellore.ac.in.ORCID http://orcid.org/0000-0002-3649-8846
Julie HephzibahDept of Nuclear Medicine, Christian Medical College, Vellore, India.
M J PaulDept of Endocrine Surgery, Christian Medical College and Hospital, Vellore, India.
Deepak Thomas AbrahamDept of Endocrine Surgery, Christian Medical College and Hospital, Vellore, India.
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aim to analyze the clinicopathological profile and outcomes of management for children with papillary thyroid carcinoma (PTC).

methodsRelevant clinical data of children ≤ 18 years of age managed for PTC between January 2006 and July 2018 as well as details of their follow-up till December 2019 were retrospectively collected and analyzed.

resultsThere were 82 children with PTC that were managed during the study period. At presentation, 39 (47.6%) had cervical lymphadenopathy, while 9 (11%) had systemic metastasis. Majority of patients 39 (47.6%) underwent total thyroidectomy with a selective neck dissection, while total thyroidectomy alone was performed in 26 (31.7%). Following surgery, hypocalcemia was seen in 39 (47.6%): 28 (34.1%) were temporary, while 11 (13.4%) were permanent. Twenty-eight (34%) developed persistent disease after surgery and

conclusionChildren with papillary thyroid cancers present with aggressive disease, 47.6% with cervical nodal metastasis and 11% with distant metastasis in this cohort. The rate of post-thyroidectomy hypocalcemia in this study is substantial, and efforts to reduce it are actively being pursued. The presence of metastatic cervical lymph node at presentation (p = 0.002) and tumor size (p = 0.014) were the only significant risk factors for persistent and metastatic disease, respectively, in this study.

Indexed as

ThyroidectomyAdolescentCarcinoma, PapillaryChildChild, PreschoolFemaleHumansLymphatic MetastasisLymph NodesMaleNeck DissectionPrognosisRetrospective StudiesThyroid Cancer, PapillaryThyroid NeoplasmsTreatment Outcome

Identifiers

PMID33078217
OpenAlexW3093065395

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.