ArticleBMJ open2020
Association between neutrophil-to-albumin ratio and mortality in patients with cardiogenic shock: a retrospective cohort study.
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of reparixin on survival in patients at high risk for in-hospital mortality: a meta-analysis of randomized trials.Frontiers in immunology · 2022Pooled it
- Association Between Neutrophil Percentage-to-Albumin Ratio (NPAR) and the Prognosis of Non-Small-Cell Lung Cancer.Cancers · 2026Article
- A Commentary on "Associations of the NPAR index with breast cancer incidence and mortality (NHANES 2001-2018)".International journal of surgery (London, England) · 2026Article
- Pan-immune inflammation value and neutrophil-to-albumin ratio predict hemorrhagic transformation after intravenous thrombolysis in acute ischemic stroke: a dual-center cohort study.Frontiers in nutrition · 2026Article
- Threshold-dependent effect of the neutrophil-to-albumin ratio (NAR) in early pregnancy: a novel insight for preeclampsia risk prediction.American journal of translational research · 2026Article
- Article
- Association Between Neutrophil Percentage-to-Albumin Ratio and 2-Year Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement.Anatolian journal of cardiology · 2025Article
- The role of neutrophils in vasospasm and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: Is it time for a SAH clinical trial targeting neutrophils?Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025Review
- The predictive implications for stroke-associated infection and prognostic outcome of neutrophil to albumin ratio in Chinese patients with spontaneous intracerebral hemorrhage.Annals of medicine · 2025Article
- Predictive value of neutrophil-to-albumin ratio for the incidence of acute kidney injury in intracerebral hemorrhage patients.Neurosurgical review · 2025Article
- Inflammation-Based Hematologic Indices as Prognostic Markers in Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension: A Hypothesis-Generating Registry Study.International journal of molecular sciences · 2025Article
- Inflammatory Biomarkers and Carotid Atherosclerosis: The Predictive Role of the Neutrophil/Albumin Ratio.Medicina (Kaunas, Lithuania) · 2025Article
- NHANES-based assessment of neutrophil-percentage-to-albumin and neutrophil-to-lymphocyte ratios as moderate predictors of mortality in adults with chronic respiratory diseases.Frontiers in pharmacology · 2025Article
- Association between inflammation- and nutrition-related indicators and mortality in patients with heart failure: a cohort study.Frontiers in nutrition · 2025Article
- Association between immuno-nutritional biomarkers and mortality in hospitalized geriatric population.Frontiers in immunology · 2025Observational
- Neutrophil-to-Albumin Ratio Predicts Stroke-Associated Pneumonia in Patients with Intracerebral Hemorrhage.Journal of inflammation research · 2025Article
- Investigating nonlinear associations between neutrophil percentage to albumin ratio and cardiovascular disease: a nationally representative cross-sectional study.Scientific reports · 2024Article
- The Neutrophil-to-Albumin Ratio (NAR): A Novel Index in Relation to Clinical Symptoms, Quality of Life, and Psychological Status in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D).Journal of inflammation research · 2024Article
- Platelet-to-Albumin Ratio: The Prognostic Utility in the Prediction of 2-Month Postoperative Heart Transplant Complications.Journal of cardiovascular development and disease · 2023Article
- Does Albumin Predict the Risk of Mortality in Patients with Cardiogenic Shock?International journal of molecular sciences · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the prognostic value of neutrophil-to-albumin ratio (NAR) in critically ill patients with cardiogenic shock (CS).
designA retrospective cohort study.
settingA single centre in Boston, USA.
participants475 patients with CS were included, among which 272 (57.3%) were men and 328 (69.1%) were white. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was 90-day mortality and the secondary outcomes were 30-day and 365-day mortality.
resultsA significant positive correlation between NAR levels and 90-day, 30-day or 365-day mortality was observed. For 90-day mortality, the adjusted HR (95% CI) values given NAR levels 23.54-27.86 and >27.86 were 1.71 (1.14 to 2.55) and 1.93 (1.27 to 2.93) compared with the reference (NAR<23.47). Receiver operator characteristic curve analysis showed that NAR had a certain prognostic value in predicting 90-day mortality of CS, which was more sensitive than the neutrophil percentage or the serum albumin level alone (0.651 vs 0.509, 0.584). For the secondary outcomes, the upward trend remained statistically significant.
conclusionsNAR level was associated with the mortality of CS patients. The prognostic value of NAR was more sensitive than the neutrophil percentage or the serum albumin level alone, but not as good as Sequential Organ Failure Assessment or Simplified Acute Physiology Score.
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