Evidence map›Paper›PMID 33077568›Full record

ArticleBMJ open2020

Risks of use and non-use of antibiotics in primary care: qualitative study of prescribers' views.

Olga Boiko, Caroline Burgess, Robin Fox, Mark Ashworth, Martin C Gulliford

Abstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Review
  6. Review
  7. Lemierre syndrome: a hidden complication of sore throats.International journal of emergency medicine · 2023
    Article
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  9. Post-consultation acute respiratory tract infection recovery: a latent class-informed analysis of individual patient data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olga BoikoSchool of Population Health and Environmental Sciences, King's College London, London, UK.
Caroline BurgessSchool of Population Health and Environmental Sciences, King's College London, London, UK.
Robin FoxBicester Health Centre, Bicester, Oxfordshire, UK.
Mark AshworthSchool of Population Health and Environmental Sciences, King's College London, London, UK.ORCID 0000-0001-6514-9904
Martin C GullifordSchool of Population Health and Environmental Sciences, King's College London, London, UK martin.gulliford@kcl.ac.uk.ORCID 0000-0003-1898-9075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe emergence of antimicrobial resistance has led to increasing efforts to reduce unnecessary use of antibiotics in primary care, but potential hazards from bacterial infection continue to cause concern. This study investigated how primary care prescribers perceive risk and safety concerns associated with reduced antibiotic prescribing.

methodsQualitative study using semistructured interviews conducted with primary care prescribers from 10 general practices in an urban area and a shire town in England. A thematic analysis was conducted.

resultsThirty participants were recruited, including twenty-three general practitioners, five nurses and two pharmacists. Three main themes were identified: risk assessment, balancing treatment risks and negotiating decisions and risks. Respondents indicated that their decisions were grounded in clinical risk assessment, but this was informed by different approaches to antibiotic use, with most leaning towards reduced prescribing. Prescribers' perceptions of risk included the consequences of both inappropriate prescribing and inappropriate withholding of antibiotics. Sepsis was viewed as the most concerning potential outcome of non-prescribing, leading to possible patient harm and potential litigation. Risks of antibiotic prescribing included antibiotic resistant and

conclusionsAttitudes towards antibiotic prescribing are evolving, with reduced antibiotic prescribing now being approached more systematically. The safety trade-offs associated with either use or non-use of antibiotics present difficulties especially when prescribing decisions are inconsistent with patients' expectations.

Indexed as

Anti-Bacterial AgentsPrimary Health CareEnglandHumansInappropriate PrescribingQualitative ResearchAnti-Bacterial Agentshealth policyhealth & safetyinfectious diseasesprimary care

Identifiers

PMID33077568
PMCPMC7574941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.