Evidence map›Paper›PMID 33077519›Full record

ArticleThe Journal of biological chemistry2020

Murine GFP-Mx1 forms nuclear condensates and associates with cytoplasmic intermediate filaments: Novel antiviral activity against VSV.

Pravin B Sehgal, Huijuan Yuan, Mia F Scott, Yan Deng, Feng-Xia Liang, Andrzej Mackiewicz

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  6. Phase-Separated Subcellular Compartmentation and Related Human Diseases.International journal of molecular sciences · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Pravin B SehgalDepartments of Cell Biology and Anatomy, New York Medical College, Valhalla, New York, USA; Department of Medicine, New York Medical College, Valhalla, New York, USA. Electronic address: pravin_sehgal@nymc.edu.
Huijuan YuanDepartments of Cell Biology and Anatomy, New York Medical College, Valhalla, New York, USA.
Mia F ScottDepartments of Cell Biology and Anatomy, New York Medical College, Valhalla, New York, USA.
Yan DengDivision of Advanced Research Technologies, New York University Grossman School of Medicine, New York, New York, USA.
Feng-Xia LiangDivision of Advanced Research Technologies, New York University Grossman School of Medicine, New York, New York, USA.
Andrzej MackiewiczDepartment of Medical Biotechnology, University School of Medical Sciences, Poznań, Poland; Department of Diagnostics and Immunology of Cancer, Greater Poland Cancer Center, Poznań, Poland.
New York Medical College · USNew York University · USGreater Poland Cancer Center · PL

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
NCI NIH HHS P30 CA016087
6 · The paper itself

Abstract

Type I and III interferons induce expression of the "myxovirus resistance proteins" MxA in human cells and its ortholog Mx1 in murine cells. Human MxA forms

Indexed as

AnimalsAntiviral AgentsCell NucleusCytoplasmGreen Fluorescent ProteinsHumansIntermediate FilamentsMiceMyxovirus Resistance ProteinsRhabdoviridae InfectionsVesicular stomatitis Indiana virusAntiviral AgentsGreen Fluorescent ProteinsMx1 protein, mouseMyxovirus Resistance Proteinsanimal virusantiviral activityantiviral agentgiantin-based intermediate filamentsinterferonintermediate filamentmembraneless organelles (MLOs)Mx1MxAmyxovirus (Mx) resistance proteinsphase-separated biomolecular condensatesstress granulevesicular stomatitis virus

Identifiers

PMID33077519
PMCPMC7939456
OpenAlexW3093454445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.